Cortical pseudolaminar necrosis
In today's world, Cortical pseudolaminar necrosis has become a topic of widespread interest. From its impact on society to its relevance in the professional field, Cortical pseudolaminar necrosis has captured the attention of people of all ages and cultures. With endless opinions and perspectives surrounding Cortical pseudolaminar necrosis, it is crucial to fully analyze its implications and consequences. In this article, we will explore various aspects related to Cortical pseudolaminar necrosis, with the aim of providing a broad and complete overview of this topic. From its origin to its possible future developments, we will take a look at Cortical pseudolaminar necrosis from different angles to understand its importance today.
Cortical pseudolaminar necrosis, also known as cortical laminar necrosis and simply laminar necrosis, is the death of cells in the cerebral cortex of the brain in a band-like pattern, with a relative preservation of cells immediately adjacent to the meninges.
It is seen in the context of cerebral hypoxic-ischemic insults, e.g. status epilepticus, strokes.
Histologically, grey matter is more vulnerable than white matter to necrosis due to lack of oxygen. The third layer of the grey matter is the most vulnerable. Damage is greater in the sulci when compared to gyri of the brain.
When seen on CT scan, it shows hyperdensity in the surface of the cortex. Cortical enhancement is seen after two weeks, with maximum intensity at one to two months, and resolved after six months.
On MRI scans, early changes show low T1 intensity due to ischemic changes. There is high T1 intensity due to accumulation of neuronal damage, reactive tissue changes, and deposition of fat-laden macrophages.
See also
References
- ^ Hypoxic and Ischemic Encephalopathy. neuropathology.neoucom.edu. Accessed on: 29 December 2010.
- ^ a b c d Samain, J.; Haven, F.; Gille, M.; Mathys, P. (2011-06-18). "Typical CT and MRI features of cortical laminar necrosis". Journal of the Belgian Society of Radiology. 94 (6): 357. doi:10.5334/jbr-btr.713. ISSN 2514-8281. PMID 22338400.
External links
- Hypoxic-ischemic encephalopathy - principles (neuropathology-web.org)
- Laminar necrosis on MRI (rochester.edu)
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