Karyolysis
In today's world, Karyolysis has become a topic of great relevance and interest to a wide spectrum of people. From its impact on society to its influence on different areas of everyday life, Karyolysis has captured the attention of experts and fans alike. With a historical background and contemporary relevance, it is evident that Karyolysis is a topic that deserves to be explored in depth. In this article, we will analyze different aspects of Karyolysis and examine its impact in various areas, with the aim of providing a comprehensive view of its importance and influence in today's world.
Karyolysis (from Greek κάρυον karyon—kernel, seed, or nucleus), and λύσις lysis from λύειν lyein, "to separate") is the complete dissolution of the chromatin of a dying cell due to the enzymatic degradation by endonucleases. The whole cell will eventually stain uniformly with eosin after karyolysis. It is usually associated with karyorrhexis and occurs mainly as a result of necrosis, while in apoptosis after karyorrhexis the nucleus usually dissolves into apoptotic bodies.
Disintegration of the cytoplasm, pyknosis of the nuclei, and karyolysis of the nuclei of scattered transitional cells may be seen in urine from healthy individuals as well as in urine containing malignant cells. Cells with an attached tag of partially preserved cytoplasm were initially described by Papanicolaou and are sometimes called comet or decoy cells. They may have some of the characteristics of malignancy, and it is therefore important that they be recognized for what they are.
Additional images
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Micrograph showing karyolysis and contraction band necrosis in an individual that had a myocardial infarction (heart attack). -
Micrograph showing karyolysis and contraction band necrosis (left of image) and ischemic (nucleated) cardiac myocytes (right of image) in an individual that had a myocardial infarction.
See also
References
- ^ Cotran; Kumar, Collins (1998). Robbins Pathologic Basis of Disease. Philadelphia: W.B Saunders Company. ISBN 0-7216-7335-X.
- ^ Bibbo, Marluce (2008). Comprehensive Cytopathology (Third ed.). Elsevier Inc. pp. 409–437.
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