Pyknosis
In today's world, Pyknosis has become a topic of great relevance and interest to a wide spectrum of people, companies and organizations. Since its emergence, Pyknosis has captured the attention of society and has generated endless debates, discussions and reflections around its importance, impact and evolution. Whether on a personal, professional, social or cultural level, Pyknosis has managed to transcend borders and has established itself as a key point of reference today. For this reason, it is essential to analyze and address in a deep and detailed manner all aspects related to Pyknosis, in order to better understand its influence and relevance in our daily lives.
Pyknosis, or karyopyknosis, is the irreversible condensation of chromatin in the nucleus of a cell undergoing necrosis or apoptosis. It is followed by karyorrhexis, or fragmentation of the nucleus. Pyknosis (from Ancient Greek πυκνός meaning "thick, closed or condensed") is also observed in the maturation of erythrocytes (a red blood cell) and the neutrophil (a type of white blood cell). The maturing metarubricyte (a stage in RBC maturation) will condense its nucleus before expelling it to become a reticulocyte. The maturing neutrophil will condense its nucleus into several connected lobes that stay in the cell until the end of its cell life.
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Micrograph of an infarct in the biliary tract, with pyknotic nuclei (arrows) (400x).
Pyknotic nuclei are often found in the zona reticularis of the adrenal gland. They are also found in the keratinocytes of the outermost layer in parakeratinised epithelium.
See also
References
- ^ Kumar V, Abbas A, Nelson F, Mitchell R (2007). Robbins Basic Pathology (8th ed.). pp. 6, 9–10 (table 1-1).
- ^ Kroemer G, Galluzzi L, Vandenabeele P, Abrams J, Alnemri ES, Baehrecke EH, et al. (January 2009). "Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009". Cell Death and Differentiation. 16 (1): 3–11. doi:10.1038/cdd.2008.150. PMC 2744427. PMID 18846107.
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