Tu banner alternativo

(R)-3-Nitrobiphenyline

Nowadays, (R)-3-Nitrobiphenyline is a theme that has captured the attention of people all over the world. With its relevance in today's society, (R)-3-Nitrobiphenyline continues to be a point of discussion in different areas, from politics to popular culture. Its impact is evident on social networks, where ideas, opinions and debates about (R)-3-Nitrobiphenyline are constantly shared. As we move forward in time, (R)-3-Nitrobiphenyline remains a topical and topical topic, with a significant impact on the way people view the world around them. In this article, we will explore different perspectives on (R)-3-Nitrobiphenyline and its importance in modern society.

Tu banner alternativo
(R)-3-Nitrobiphenyline
Clinical data
MedlinePlusa682611
Identifiers
  • (R)-2--4,5-dihydro-1H-imidazole
CAS Number
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H17N3O3
Molar mass311.341 g·mol−1
3D model (JSmol)
  • c2ccc((=O)=O)cc2-c1ccccc1OC(C)C3=NCCN3
  • InChI=1S/C17H17N3O3/c1-12(17-18-9-10-19-17)23-16-8-3-2-7-15(16)13-5-4-6-14(11-13)20(21)22/h2-8,11-12H,9-10H2,1H3,(H,18,19)/t12-/m1/s1 checkY
  • Key:NMSAVNXFCXMJJY-GFCCVEGCSA-N checkY
  (verify)

(R)-3-Nitrobiphenyline is a drug. As an α2-adrenergic agonist, it activates α2 adrenergic receptors, which respond to the hormones adrenaline (also known as epinephrine) and noradrenaline (norepinephrine). It is selective for the α2C subtype, as well as being a weak antagonist at the α2A and α2B subtypes. It has been used in scientific research to characterize the binding and functional properties of the α2C subtype.[1][2]

References

  1. ^ Crassous PA, Cardinaletti C, Carrieri A, Bruni B, Di Vaira M, Gentili F, et al. (August 2007). "Alpha2-adrenoreceptors profile modulation. 3.1 (R)-(+)-m-nitrobiphenyline, a new efficient and alpha2C-subtype selective agonist". Journal of Medicinal Chemistry. 50 (16): 3964–3968. doi:10.1021/jm061487a. PMID 17630725.
  2. ^ Del Bello F, Mattioli L, Ghelfi F, Giannella M, Piergentili A, Quaglia W, et al. (November 2010). "Fruitful adrenergic α(2C)-agonism/α(2A)-antagonism combination to prevent and contrast morphine tolerance and dependence". Journal of Medicinal Chemistry. 53 (21): 7825–7835. doi:10.1021/jm100977d. PMID 20925410.
Stub icon

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

Wikious
Boobota
Sagapedia