Cervical conization
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| Cervical conization | |
|---|---|
| ICD-9-CM | 67.2 |
Cervical conization refers to an excision of a cone-shaped portion of tissue from the mucous membrane of the cervix. Conization is used for diagnostic purposes as part of a biopsy and for therapeutic purposes to remove pre-cancerous cells (cervical intraepithelial neoplasia) or early stage cervical cancer.
- Cold knife conization (CKC)
- Laser conization
- Loop electrical excision procedure (LEEP)
Side effects
Cervical conization effectively reduces the risk of cancer developing or spreading but it causes an increased risk of premature birth in future pregnancies.
The chances of cancer recurrence and premature birth depends on the type of conization. Cold knife conization is associated with 7% chance of the cancer recurring and 16% chance of premature birth, laser conisation comes with 6% cancer recurrence and 13% premature birth, and loop excision comes with 10% recurrence and 11% premature birth.
See also
References
- ^ Cooper, Danielle B.; Carugno, Jose; Menefee, Gary W. (2023), "Conization of Cervix", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 28722875, retrieved 2023-11-16
- ^ a b c Athanasiou, Antonios; Veroniki, Areti Angeliki; Efthimiou, Orestis; Kalliala, Ilkka; Naci, Huseyin; Bowden, Sarah; Paraskevaidi, Maria; Arbyn, Marc; Lyons, Deirdre; Martin-Hirsch, Pierre; Bennett, Phillip; Paraskevaidis, Evangelos; Salanti, Georgia; Kyrgiou, Maria (2022-07-25). "Comparative effectiveness and risk of preterm birth of local treatments for cervical intraepithelial neoplasia and stage IA1 cervical cancer: a systematic review and network meta-analysis". The Lancet Oncology. 23 (8): 1097–1108. doi:10.1016/S1470-2045(22)00334-5. PMC 9630146. PMID 35835138.
- ^ a b c "Prevention of cervical cancer: what are the risks and benefits of different treatments?". NIHR Evidence (Plain English summary). National Institute for Health and Care Research. 2023-11-10. doi:10.3310/nihrevidence_60599. S2CID 265201829.
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