Dinitrosyl iron complex

In this article, we will delve into the topic of Dinitrosyl iron complex, exploring its different facets and its relevance today. _Var1 is a topic that has aroused great interest in different areas, from science to popular culture, and its impact has been significant on society. Throughout history, Dinitrosyl iron complex has played a fundamental role in people's lives, influencing their decisions, their beliefs, and their way of interacting with the world around them. Furthermore, Dinitrosyl iron complex has been the subject of debate and analysis on numerous occasions, which has contributed to enriching our understanding of this particular issue. In the next lines, we will examine in detail the various aspects of Dinitrosyl iron complex and their importance in the current context.

In biochemistry, dinitrosyl iron complexes (DNIC's) are coordination complexes with the formula ⁻. Together with Roussin esters (Fe₂(NO)₄(SR)₂), they result from the degradation of iron-sulfur proteins by nitric oxide. Commonly the thiolate ligands are cysteinyl residues or glutathione. These metal nitrosyl complexes have attracted much attention because they serve as biochemical signals in response to oxidative stress, manifested in the formation of NO. The anions are tetrahedral.^[1][2]

References

1. ^ Crack, J. C.; Green, J.; Thomson, A. J.; Brun, N. E. L. (2014). "Iron–Sulfur Clusters as Biological Sensors: The Chemistry of Reactions with Molecular Oxygen and Nitric Oxide". Accounts of Chemical Research. 47 (10): 3196–3205. doi:10.1021/ar5002507. PMID 25262769.
2. ^ Jessica Fitzpatrick; Eunsuk Kim (2015). "Synthetic Modeling Chemistry of Iron–Sulfur Clusters in Nitric Oxide Signaling". Acc. Chem. Res. 48 (8): 2453–2461. doi:10.1021/acs.accounts.5b00246. PMID 26197209.