In the EPRS world, there are endless aspects that deserve to be explored and discussed. Whether EPRS is a person, a topic, a date or any other concept, its relevance and impact on our lives become evident as we delve deeper into its meaning and repercussions. From its origin to its evolution over time, EPRS has left its mark on society, culture and history, generating debates, reflections and analyzes that allow us to better understand its importance. In this article, we will delve into the world of EPRS to discover its many facets and learn more about its meaning in our current context.
Bifunctional aminoacyl-tRNA synthetase is an enzyme that in humans is encoded by the EPRSgene.
Gene
Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined.
Function
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species.
Phosphorylation of EPRS is reported to be essential for the formation of GAIT (Gamma-interferon Activated Inhibitor of Translation) complex that regulates the translation of multiple genes in monocytes and macrophages.
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