Lokivetmab

Nowadays, Lokivetmab is a topic that has captured the attention of many people around the world. From its impact on society to its influence on the economy, Lokivetmab is a topic that has become increasingly relevant in everyday conversations. With the increasing importance of Lokivetmab, it is crucial to understand its scope and implications in different aspects of life. In this article, we will thoroughly explore Lokivetmab and analyze its impact on our modern society. From its origins to its possible future developments, we will delve into the fascinating world of Lokivetmab and discover its true meaning in today's world.

Lokivetmab
Monoclonal antibody
TypeWhole antibody
Targetinterleukin 31 (IL-31)
Clinical data
Trade namesCytopoint
Routes of
administration
subcutaneous injection
ATCvet code
Legal status
Legal status
  • veterinary use
Identifiers
CAS Number
UNII

Lokivetmab, trade name Cytopoint, is a monoclonal antibody used to treat atopic dermatitis in dogs. It acts against interleukin 31 (IL-31), which is a cytokine involved in causing itchiness (pruritus). Lokivetmab is administered by subcutaneous injection; each dose is effective for four to eight weeks.

The United States Department of Agriculture (USDA) approved lokivetmab (manufactured by Zoetis and sold under the trade name Cytopoint) in December 2016, and it was approved by the European Medicines Agency in 2017. Lokivetmab was the first monoclonal antibody to be approved for use in animals in the European Union.

References

  1. ^ "Zoetis earns license for Cytopoint skin therapy". Veterinary Practice News. 4 January 2017. Retrieved 2018-07-06.
  2. ^ a b Marsella R, De Benedetto A (July 2017). "Atopic Dermatitis in Animals and People: An Update and Comparative Review". Veterinary Sciences. 4 (3): 37. doi:10.3390/vetsci4030037. PMC 5644664. PMID 29056696.
  3. ^ a b McKay L (13 July 2017). "Making a difference for dogs with atopic dermatitis: When to use Apoquel and when to use Cytopoint". dvm360.com. Retrieved 2018-07-07.
  4. ^ a b "First antibody therapy in veterinary medicine launched for dogs in the UK". The Veterinary Record. 181 (1): 6–7. July 2017. doi:10.1136/vr.j3147. PMID 28667135. S2CID 20166012.

External links

  • "Lokivetmab". Drug Information Portal. U.S. National Library of Medicine.