Nowadays, Nicotinyl alcohol is a topic that has captured the attention of many people around the world. With its relevance and impact on society, Nicotinyl alcohol has become a point of interest for industries, governments and academics alike. From its inception to its current evolution, Nicotinyl alcohol has been the subject of study, debate and innovation, leading to greater knowledge and understanding of its importance. In this article, we will explore the different facets of Nicotinyl alcohol, analyzing its impact on various aspects of everyday life and its influence on future development.
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Clinical data | |
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Other names | Roniacol; Roniacol tartrate; Nicotinyl tartrate; Nicotinyl alcohol tartrate; Nicotinic alcohol; Pyridylcarbinol |
AHFS/Drugs.com | Monograph |
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ECHA InfoCard | 100.002.604 |
Chemical and physical data | |
Formula | C6H7NO |
Molar mass | 109.128 g·mol−1 |
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Nicotinyl alcohol (pyridylcarbinol) is a niacin derivative used as a hypolipidemic agent and as a vasodilator. It causes flushing and may decrease blood pressure.
It appears as a crystal that dissolves in water and alcohol with ease, also soluble in ether; melting range 147–148 °C.[citation needed]
Nicotinic acid is a brief peripheral vasodilator; this compound was made to make its action longer and effective. It provokes cutaneous flushing in head and upper thorax with heat, but with no major effects in blood pressure. It is used in peripheral vascular diseases, like arteriosclerosis obliterans, Raynaud's disease, thromboangiitis obliterans (Buerger's disease), arterial embolism, chilblains or migraine associated with vascular spasm.
Fischer and Tebrock worked with this drug in more than two hundred patients for more than three years, achieving effective improvements, mainly in symptoms related to intermittent claudication, ulcer healing and others.
At least a couple of uses for this agent were discovered over the years: