Osaterone

This article will address the topic of Osaterone, a matter of great relevance and interest today. Osaterone has captured the attention of experts and the general public due to its impact on various areas of society. Along these lines, different aspects related to Osaterone will be examined, from its origin and evolution, to its implications in the contemporary world. The opinions and positions of specialists in the matter will also be analyzed, as well as the possible solutions or measures to be taken regarding this issue. Without a doubt, Osaterone is a topic that leaves no one indifferent, so it is essential to deepen its study and understanding to achieve a more complete and clarifying vision.

This article is about a non-clinically used antiandrogen compound. For the pharmaceutical drug, see osaterone acetate.
Osaterone
Clinical data
Other namesTZP-5258; Gestoxarone; 2-Oxachloromadinone; 17α-Hydroxy-6-chloro-2-oxa-6-dehydroprogesterone; 17α-Hydroxy-6-chloro-2-oxapregna-4,6-diene-3,20-dione
Identifiers
  • (1R,3aS,3bR,9aR,9bS,11aS)-1-acetyl-5-chloro-1-hydroxy-9a,11a-dimethyl-2,3,3a,3b,9,9b,10,11-octahydroindenoisochromen-7-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H25ClO4
Molar mass364.87 g·mol−1
3D model (JSmol)
  • CC(=O)1(CC21(CC32C=C(C4=CC(=O)OC34C)Cl)C)O
  • InChI=1S/C20H25ClO4/c1-11(22)20(24)7-5-14-12-8-16(21)15-9-17(23)25-10-18(15,2)13(12)4-6-19(14,20)3/h8-9,12-14,24H,4-7,10H2,1-3H3/t12-,13+,14+,18-,19+,20+/m1/s1
  • Key:ZLLOIFNEEWYATC-XMUHMHRVSA-N

Osaterone (developmental code name TZP-5258), also known as 17α-hydroxy-6-chloro-2-oxa-6-dehydroprogesterone, as well as 2-oxachloromadinone, is a steroidal antiandrogen and progestin that was never marketed. The C17α acetate ester of osaterone, osaterone acetate, in contrast, has been marketed.

See also

References

  1. ^ a b Index Nominum: International Drug Directory. MedPharm. 2011. ISBN 978-3-8047-5053-1.
  2. ^ a b Milne GW (8 May 2018). Drugs: Synonyms and Properties: Synonyms and Properties. Taylor & Francis. pp. 969–. ISBN 978-1-351-78989-9.



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