In today's world, Pinoresinol has taken a fundamental role in various areas of society. From its impact on technology to its influence on the social sphere, Pinoresinol has marked a before and after in our way of living and relating. Over time, Pinoresinol has been the subject of study and debate, generating both admiration and controversy. In this article, we will thoroughly explore the impact of Pinoresinol in different areas, seeking to understand its importance in the contemporary world and its relevance for the future.
Pinoresinol is a tetrahydrofuran lignan found in Styrax sp.,Forsythia suspensa, and in Forsythia koreana. It is also found in the caterpillar of the cabbage butterfly, Pieris rapae where it serves as a defence against ants.
In food, it is found in sesame seed, in Brassica vegetables and in olive oil. Pinoresinol has also been found to be toxic to larvae of the milkweed bug Oncopeltus fasciatus and of the haematophagous insect Rhodnius prolixus, which is a vector of chagas disease.
Currently, pinoresinol is isolated from plants with low efficiency and low yield.
Pinoresinol inhibits the enzyme α-glucosidasein vitro and may therefore act as a hypoglycemic agent. A study involving extra virgin olive oil showed that pinoresinol possess in vitro chemoprevention properties. Increased apoptosis and cellular arrest at the G2/M stage in p53-proficient cells occurred. Pinoresinol of olive oil decreases vitamin D intestinal absorption.
Metabolism into enterolignans
Pinoresinol, along with other plant lignans, are converted into enterolignans by intestinal microflora in the human body.
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