Streptomyces avermitilis

In this article, we will explore the fascinating world of Streptomyces avermitilis, a topic that has captivated the attention of millions of people around the world. Streptomyces avermitilis has been the subject of multiple studies and research over the years, and its impact on modern society is undeniable. Since its discovery, Streptomyces avermitilis has generated endless debates and controversies, awakening unprecedented interest in various areas of knowledge. Throughout the next lines, we will delve into the most relevant details about Streptomyces avermitilis, exploring its history, its influence today and the future perspectives it offers. It doesn't matter if you are an expert on the subject or just curious, this article will give you an enriching and complete look at Streptomyces avermitilis.

Streptomyces avermitilis
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Actinomycetota
Class: Actinomycetia
Order: Streptomycetales
Family: Streptomycetaceae
Genus: Streptomyces
Species:
S. avermitilis
Binomial name
Streptomyces avermitilis
(ex Burg et al. 1979) Kim and Goodfellow 2002
Strains

Streptomyces avermitilis MA-4680

Synonyms

Streptomyces avermectinius Takahashi et al. 2002

Streptomyces avermitilis is a species of bacteria in the genus Streptomyces. This bacterium was discovered by Satoshi Ōmura in Shizuoka Prefecture, Japan.

The first complete genome sequence of S. avermitilis was completed in 2003. The genome consists of a single chromosome with a linear structure, unlike most bacterial genomes, which exist in the form of circular chromosomes.

Avermectins are industrially derived from the fermentation products of S. avermitilis. Avermectin itself was discovered by the Satoshi Ōmura group and first disclosed in Burg et al. 1979. One of the most widely employed drugs against nematode and arthropod infestations is the avermectin derivative ivermectin, as well as abamectin, a widely used insecticide and antihelmintic.

See also

References

  1. ^ a b c Burg, R. W.; Miller, B. M.; Baker, E. E.; Birnbaum, J.; Currie, S. A.; Hartman, R.; Kong, Y. L.; Monaghan, R. L.; Olson, G.; Putter, I.; Tunac, J. B.; Wallick, H.; Stapley, E. O.; Oiwa, R.; Omura, S. (1979). "Avermectins, new family of potent anthelmintic agents: Producing organism and fermentation". Antimicrobial Agents and Chemotherapy. 15 (3): 361–367. doi:10.1128/AAC.15.3.361. PMC 352666. PMID 464561.
  2. ^ Kim, S. B.; Goodfellow, M. (2002). "Streptomyces avermitilis sp. nov., nom. Rev., a taxonomic home for the avermectin-producing streptomycetes". International Journal of Systematic and Evolutionary Microbiology. 52 (Pt 6): 2011–2014. doi:10.1099/ijs.0.02265-0. PMID 12508861.
  3. ^ Takahashi, Y.; Matsumoto, A.; Seino, A.; Ueno, J.; Iwai, Y.; Omura, S. (2002). "Streptomyces avermectinius sp. nov., an avermectin-producing strain". International Journal of Systematic and Evolutionary Microbiology. 52 (Pt 6): 2163–2168. doi:10.1099/ijs.0.02237-0. PMID 12508884.
  4. ^ Ikeda H, Ishikawa J, Hanamoto A, Shinose M, Kikuchi H, Shiba T, Sakaki Y, Hattori M, Omura S (2003). "Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis". Nat. Biotechnol. 21 (5): 526–531. doi:10.1038/nbt820. PMID 12692562.
  5. ^ Paul Dyson (1 January 2011). Streptomyces: Molecular Biology and Biotechnology. Horizon Scientific Press. p. 5. ISBN 978-1-904455-77-6. Retrieved 16 January 2012.
  6. ^ a b Martín, Juan F; Rodríguez-García, Antonio; Liras, Paloma (2017-03-15). "The master regulator PhoP coordinates phosphate and nitrogen metabolism, respiration, cell differentiation and antibiotic biosynthesis: comparison in Streptomyces coelicolor and Streptomyces avermitilis". The Journal of Antibiotics. 70 (5). Japan Antibiotics Research Association (Nature Portfolio): 534–541. doi:10.1038/ja.2017.19. ISSN 0021-8820. PMID 28293039. S2CID 1881648.

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