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VectorBase

Nowadays, VectorBase is a topic of great importance that generates great interest in society. Since its origins, VectorBase has been the subject of study and debate, attracting the attention of specialists, researchers and people interested in understanding its implications and repercussions. As time progresses, VectorBase has been evolving and adapting to changes in the environment, always remaining present on the public agenda. In this article, we will explore different perspectives and approaches related to VectorBase, analyzing its impact on different aspects of everyday life.

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VectorBase[1][2] is one of the five Bioinformatics Resource Centers (BRC) funded by the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH), which is an agency of the United States Department of Health and Human Services. VectorBase is focused on invertebrate vectors of human pathogens working with the sequencing centers and the research community to curate vector genomes (mainly genome annotation).

Genomes covered in the VectorBase database

Tools available through the VectorBase site

  • Genome browser
  • Community annotation system
  • Microarray and gene expression repository
  • Controlled vocabularies for anatomy,[5] insecticide resistance and vector-borne diseases (malaria and dengue fever)
  • BLAST searches for all covered genomes

See also

References

  1. ^ Lawson, D; Arensburger, P; Atkinson, P; Besansky, NJ; Bruggner, RV; Butler, R; Campbell, KS; Christophides, GK; et al. (2007). "VectorBase: a home for invertebrate vectors of human pathogens". Nucleic Acids Research. 35 (Database issue): D503–5. doi:10.1093/nar/gkl960. PMC 1751530. PMID 17145709.
  2. ^ Lawson, D; Arensburger, P; Atkinson, P; Besansky, NJ; Bruggner, RV; Butler, R; Campbell, KS; Christophides, GK; et al. (2009). "VectorBase: a data resource for invertebrate vector genomics". Nucleic Acids Research. 37 (Database issue): D583–7. doi:10.1093/nar/gkn857. PMC 2686483. PMID 19028744.
  3. ^ Nene, V; Wortman, JR; Lawson, D; Haas, B; Kodira, C; Tu, ZJ; Loftus, B; Xi, Z; et al. (2007). "Genome sequence of Aedes aegypti, a major arbovirus vector". Science. 316 (5832): 1718–23. Bibcode:2007Sci...316.1718N. doi:10.1126/science.1138878. PMC 2868357. PMID 17510324.
  4. ^ Holt, RA; Subramanian, GM; Halpern, A; Sutton, GG; Charlab, R; Nusskern, DR; Wincker, P; Clark, AG; et al. (2002). "The genome sequence of the malaria mosquito Anopheles gambiae". Science. 298 (5591): 129–49. Bibcode:2002Sci...298..129H. CiteSeerX 10.1.1.149.9058. doi:10.1126/science.1076181. PMID 12364791. S2CID 4512225.
  5. ^ Topalis, P; Tzavlaki, C; Vestaki, K; Dialynas, E; Sonenshine, DE; Butler, R; Bruggner, RV; Stinson, EO; et al. (2008). "Anatomical ontologies of mosquitoes and ticks, and their web browsers in VectorBase". Insect Molecular Biology. 17 (1): 87–9. doi:10.1111/j.1365-2583.2008.00781.x. PMID 18237287. S2CID 8618269.
VectorBase genome browsers
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