CSF1 |
Нинди таксонда бар |
H. sapiens |
Кодирующий ген |
CSF1[d] |
Молекулярная функция |
связывание с белками плазмы, macrophage colony-stimulating factor receptor binding, гомодимеризация белка, growth factor activity, cytokine activity, связывание похожих белков һәм cytokine activity |
Күзәнәк компоненты |
часть мембраны, perinuclear region of cytoplasm, CSF1-CSF1R complex, мембрана, внеклеточное пространство, endoplasmic reticulum lumen, внеклеточная область, күзәнәк мембраны һәм внеклеточное пространство |
Биологический процесс |
positive regulation of microglial cell migration, дифференцировка клеток, positive regulation of protein metabolic process, mammary gland fat development, branching involved in mammary gland duct morphogenesis, transmembrane receptor protein tyrosine kinase signaling pathway, immune system process, positive regulation of Ras protein signal transduction, positive regulation of macrophage colony-stimulating factor signaling pathway, mammary duct terminal end bud growth, monocyte activation, positive regulation of macrophage derived foam cell differentiation, positive regulation of gene expression, macrophage colony-stimulating factor signaling pathway, positive regulation of odontogenesis of dentin-containing tooth, позитивная регуляция пролиферации клеток, regulation of macrophage derived foam cell differentiation, positive regulation of multicellular organism growth, homeostasis of number of cells within a tissue, regulation of ossification, воспалительная реакция, positive regulation of macrophage chemotaxis, врождённый иммунитет, positive regulation of mononuclear cell proliferation, osteoclast proliferation, positive regulation of osteoclast differentiation, positive regulation of cell migration, positive regulation of monocyte differentiation, positive regulation of protein kinase activity, процесс развития, связанный с репродукцией, positive regulation of cell-matrix adhesion, positive regulation of macrophage differentiation, пролиферация, macrophage differentiation, посттрансляционная модификация, regulation of signaling receptor activity, cytokine-mediated signaling pathway, гемопоэз, osteoclast differentiation, positive regulation of macrophage differentiation, osteoclast differentiation, response to ischemia, microglial cell proliferation, negative regulation of neuron death һәм positive regulation of gene expression |
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CSF1 (ингл. ) — аксымы, шул ук исемдәге ген тарафыннан кодлана торган югары молекуляр органик матдә.
Искәрмәләр
- ↑ 1,0 1,1 UniProt
- ↑ Longnecker R. Multipronged attenuation of macrophage-colony stimulating factor signaling by Epstein-Barr virus BARF1 // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — , USA: National Academy of Sciences , 2012. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.1205309109 — PMID:22826234
- ↑ Verstraete K., Elegheert J., Callewaert N. Structure and Assembly Mechanism of the Signaling Complex Mediated by Human CSF-1 // Structure / C. D. Lima — Cell Press, Elsevier BV, 2015. — ISSN 0969-2126; 1878-4186 — doi:10.1016/J.STR.2015.06.019 — PMID:26235028
- ↑ Dricot A., Barabási A., Tavernier J. et al. A proteome-scale map of the human interactome network // Cell — Cell Press, Elsevier BV, 2014. — ISSN 0092-8674; 1097-4172 — doi:10.1016/J.CELL.2014.10.050 — PMID:25416956
- ↑ 5,0 5,1 5,2 5,3 5,4 5,5 5,6 Cerretti D. P., J Wignall, D Anderson et al. Human macrophage-colony stimulating factor: alternative RNA and protein processing from a single gene // Molecular Immunology — Elsevier BV, 1988. — ISSN 0161-5890; 1872-9142 — doi:10.1016/0161-5890(88)90112-5 — PMID:2460758
- ↑ 6,0 6,1 6,2 Chen X., Liu H., Focia P. J. et al. Structure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinases // Proc. Natl. Acad. Sci. U.S.A. / M. R. Berenbaum — , USA: National Academy of Sciences , 2008. — ISSN 0027-8424; 1091-6490 — doi:10.1073/PNAS.0807762105 — PMID:19017797
- ↑ 7,00 7,01 7,02 7,03 7,04 7,05 7,06 7,07 7,08 7,09 7,10 7,11 7,12 7,13 7,14 7,15 7,16 7,17 7,18 7,19 7,20 7,21 7,22 7,23 7,24 7,25 7,26 7,27 7,28 7,29 7,30 7,31 7,32 7,33 7,34 7,35 7,36 7,37 7,38 7,39 7,40 7,41 7,42 GOA
- ↑ Manos M. M. Expression and processing of a recombinant human macrophage colony-stimulating factor in mouse cells // Mol. Cell. Biol. — ASM, 1988. — ISSN 0270-7306; 1098-5549; 1067-8824 — doi:10.1128/MCB.8.11.5035 — PMID:3264878
- ↑ 9,0 9,1 9,2 9,3 Chuan F. C., Pollard J. W., Pampfer S et al. Expression of colony-stimulating factor-1 (CSF-1) messenger RNA in human endometrial glands during the menstrual cycle: molecular cloning of a novel transcript that predicts a cell surface form of CSF-1, Expression of Colony-Stimulating Factor-1 (CSF-1) Messenger RNA in Human Endometrial Glands during the Menstrual Cycle: Molecular Cloning of a Novel Transcript That Predicts a Cell Surface Form oF CSF-1 // Molecular Endocrinology — Endocrine Society, OUP, 1991. — ISSN 0888-8809; 1944-9917 — doi:10.1210/MEND-5-12-1931 — PMID:1791839
- ↑ 10,0 10,1 10,2 10,3 10,4 GOA
- ↑ R Moriggl, Marine J. C. Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation // Genes Dev. — Cold Spring Harbor Laboratory Press, 2000. — ISSN 0890-9369; 1549-5477 — PMID:10652277
- ↑ Verstraete K., Tarbouriech N., Elegheert J. et al. Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1 // Nat. Struct. Mol. Biol. — USA: NPG, 2012. — ISSN 1545-9993; 1545-9985 — doi:10.1038/NSMB.2367 — PMID:22902366
- ↑ Craenenbroeck K. V., Desfosses A., Verstraete K. et al. Extracellular complexes of the hematopoietic human and mouse CSF-1 receptor are driven by common assembly principles // Structure / C. D. Lima — Cell Press, Elsevier BV, 2011. — ISSN 0969-2126; 1878-4186 — doi:10.1016/J.STR.2011.10.012 — PMID:22153499
- ↑ 14,0 14,1 R Moriggl, Marine J. C. Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation // Genes Dev. — Cold Spring Harbor Laboratory Press, 2000. — ISSN 0890-9369; 1549-5477 — PMID:10652277
- ↑ 15,0 15,1 15,2 15,3 Clinton S. K., R. Underwood, L. Hayes et al. Macrophage colony-stimulating factor gene expression in vascular cells and in experimental and human atherosclerosis // Am. J. Pathol. — Elsevier BV, 1992. — ISSN 0002-9440; 1525-2191; 0097-3599 — PMID:1739124
- ↑ 16,0 16,1 Cerretti D. P., J Wignall, D Anderson et al. Human macrophage-colony stimulating factor: alternative RNA and protein processing from a single gene // Molecular Immunology — Elsevier BV, 1988. — ISSN 0161-5890; 1872-9142 — doi:10.1016/0161-5890(88)90112-5 — PMID:2460758
- ↑ 17,0 17,1 17,2 Livstone M. S., Thomas P. D., Lewis S. E. et al. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium // Brief. Bioinform. — OUP, 2011. — ISSN 1467-5463; 1477-4054 — doi:10.1093/BIB/BBR042 — PMID:21873635
- ↑ 18,0 18,1 18,2 18,3 Stoecker K., Weigelt K., Ebert S. et al. Induction of STAP-1 promotes neurotoxic activation of microglia // Biochem. Biophys. Res. Commun. — Academic Press, Elsevier BV, 2009. — ISSN 0006-291X; 1090-2104 — doi:10.1016/J.BBRC.2008.12.021 — PMID:19100238
- ↑ 19,0 19,1 19,2 19,3 19,4 19,5 Thomassen M. J., Farver C. F. Peroxisome proliferator-activated receptor-gamma regulates the expression of alveolar macrophage macrophage colony-stimulating factor // J. Immunol. — Baltimore: 2008. — ISSN 0022-1767; 1550-6606 — doi:10.4049/JIMMUNOL.181.1.235 — PMID:18566389
- ↑ Ley K. Induction of dendritic cell-like phenotype in macrophages during foam cell formation // Physiological Genomics — 2007. — ISSN 1094-8341; 1531-2267 — doi:10.1152/PHYSIOLGENOMICS.00051.2006 — PMID:17244792
- ↑ 21,0 21,1 B Scheuerer, M Ernst, I Dürrbaum-Landmann et al. The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages // Blood — American Society of Hematology, Elsevier BV, 2000. — ISSN 0006-4971; 1528-0020 — PMID:10666185
- ↑ Matsumoto M., Kogawa M., Wada S. et al. Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1 // J. Biol. Chem. / L. M. Gierasch — Baltimore : American Society for Biochemistry and Molecular Biology, 2004. — ISSN 0021-9258; 1083-351X; 1067-8816 — doi:10.1074/JBC.M408795200 — PMID:15304486
- ↑ Cassani B., Rogers M. J., Villa A. et al. Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations // Am. J. Hum. Genet. — Cell Press, Elsevier BV, 2008. — ISSN 0002-9297; 1537-6605 — doi:10.1016/J.AJHG.2008.06.015 — PMID:18606301
- ↑ Cassani B., Rogers M. J., Villa A. et al. Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations // Am. J. Hum. Genet. — Cell Press, Elsevier BV, 2008. — ISSN 0002-9297; 1537-6605 — doi:10.1016/J.AJHG.2008.06.015 — PMID:18606301
- ↑ 25,0 25,1 Maysinger D Colony stimulating factor-1 potentiates neuronal survival in cerebral cortex ischemic lesion. // Acta Neuropathol. (Berl) — Springer Science+Business Media, 1996. — ISSN 0001-6322; 1432-0533 — doi:10.1007/S004010050550 — PMID:8922060
- ↑ HUGO Gene Nomenclature Commitee, HGNC:29223 (ингл.). әлеге чыганактан 2015-10-25 архивланды. 18 сентябрь, 2017 тикшерелгән.
- ↑ UniProt, Q9ULJ7 (ингл.). 18 сентябрь, 2017 тикшерелгән.
Чыганаклар
- Степанов В.М. (2005). Молекулярная биология. Структура и функция белков. Москва: Наука. ISBN 5-211-04971-3.(рус.)
- Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter (2002). Molecular Biology of the Cell (вид. 4th). Garland. ISBN 0815332181.(ингл.)