YIPF5

YIPF5
Identifikatori
Aliasi	YIPF5
Vanjski ID-jevi	OMIM: 611483 MGI: 1914430 HomoloGene: 56969 GeneCards: YIPF5
Lokacija gena (čovjek)
Hrom.	Hromosom 5 (čovjek)
Kraj	144,170,714 bp
Lokacija gena (miš)
Hrom.	Hromosom 18 (miš)
Kraj	40,352,482 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• GO:0001948, GO:0016582 vezivanje za proteine;
Ćelijska komponenta	• integral component of membrane; • COPII-coated ER to Golgi transport vesicle; • nuclear outer membrane-endoplasmic reticulum membrane network; • endoplasmic reticulum membrane; • membrana; • GO:0016023 citoplazmatska vezikula; • endoplasmic reticulum exit site; • nukleoplazma; • Endoplazmatski retikulum; • Golđijev aparat; • intracellular membrane-bounded organelle;
Biološki proces	• protein transport; • regulation of ER to Golgi vesicle-mediated transport; • vesicle-mediated transport;
	Izvori:Amigo / QuickGO
Ortolozi
	81555
	67180
	ENSG00000145817
	ENSMUSG00000024487
	Q969M3
	Q9EQQ2
	NM_030799; NM_001024947; NM_001271732
	NM_023311
	NP_001020118; NP_001258661; NP_110426
	NP_075800
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Protein YIPF5 je protein koji je kod ljudi kodiran genom YIPF5.

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 257 aminokiselina, a molekulska težina 27.989 Da.

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MSGFENLNTD	FYQTSYSIDD	QSQQSYDYGG	SGGPYSKQYA	GYDYSQQGRF
VPPDMMQPQQ	PYTGQIYQPT	QAYTPASPQP	FYGNNFEDEP	PLLEELGINF
DHIWQKTLTV	LHPLKVADGS	IMNETDLAGP	MVFCLAFGAT	LLLAGKIQFG
YVYGISAIGC	LGMFCLLNLM	SMTGVSFGCV	ASVLGYCLLP	MILLSSFAVI
FSLQGMVGII	LTAGIIGWCS	FSASKIFISA	LAMEGQQLLV	AYPCALLYGV
FALISVF

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000145817 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024487 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A (Oct 2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Research. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
^ Yoshida Y, Suzuki K, Yamamoto A, Sakai N, Bando M, Tanimoto K, Yamaguchi Y, Sakaguchi T, Akhter H, Fujii G, Yoshimura S, Ogata S, Sohda M, Misumi Y, Nakamura N (Nov 2008). "YIPF5 and YIF1A recycle between the ER and the Golgi apparatus and are involved in the maintenance of the Golgi structure". Experimental Cell Research. 314 (19): 3427–43. doi:10.1016/j.yexcr.2008.07.023. PMID 18718466.
^ "Entrez Gene: YIPF5 Yip1 domain family, member 5".
^ "UniProt, Q969M3" (jezik: engleski). Pristupljeno 13. 10. 2021.

Dopunska literatura

Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (Oct 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Tang BL, Ong YS, Huang B, Wei S, Wong ET, Qi R, Horstmann H, Hong W (Oct 2001). "A membrane protein enriched in endoplasmic reticulum exit sites interacts with COPII". The Journal of Biological Chemistry. 276 (43): 40008–17. doi:10.1074/jbc.M106189200. PMID 11489904.
Wan D, Gong Y, Qin W, Zhang P, Li J, Wei L, Zhou X, Li H, Qiu X, Zhong F, He L, Yu J, Yao G, Jiang H, Qian L, Yu Y, Shu H, Chen X, Xu H, Guo M, Pan Z, Chen Y, Ge C, Yang S, Gu J (Nov 2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proceedings of the National Academy of Sciences of the United States of America. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874.
Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ (Jan 2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nature Biotechnology. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455. S2CID 7200157.
Chen CZ, Calero M, DeRegis CJ, Heidtman M, Barlowe C, Collins RN (Dec 2004). "Genetic analysis of yeast Yip1p function reveals a requirement for Golgi-localized rab proteins and rab-Guanine nucleotide dissociation inhibitor". Genetics. 168 (4): 1827–41. doi:10.1534/genetics.104.032888. PMC 1448722. PMID 15611160.
Stolle K, Schnoor M, Fuellen G, Spitzer M, Engel T, Spener F, Cullen P, Lorkowski S (maj 2005). "Cloning, cellular localization, genomic organization, and tissue-specific expression of the TGFbeta1-inducible SMAP-5 gene". Gene. 351: 119–30. doi:10.1016/j.gene.2005.03.012. PMID 15922870.
Jin C, Zhang Y, Zhu H, Ahmed K, Fu C, Yao X (Aug 2005). "Human Yip1A specifies the localization of Yif1 to the Golgi apparatus". Biochemical and Biophysical Research Communications. 334 (1): 16–22. doi:10.1016/j.bbrc.2005.06.051. PMID 15990086.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000145817 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000024487 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12975309-5] Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A (Oct 2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Research. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.

[pmid18718466-6] Yoshida Y, Suzuki K, Yamamoto A, Sakai N, Bando M, Tanimoto K, Yamaguchi Y, Sakaguchi T, Akhter H, Fujii G, Yoshimura S, Ogata S, Sohda M, Misumi Y, Nakamura N (Nov 2008). "YIPF5 and YIF1A recycle between the ER and the Golgi apparatus and are involved in the maintenance of the Golgi structure". Experimental Cell Research. 314 (19): 3427–43. doi:10.1016/j.yexcr.2008.07.023. PMID 18718466.

[entrez-7] "Entrez Gene: YIPF5 Yip1 domain family, member 5".

[UniProt-8] "UniProt, Q969M3" (jezik: engleski). Pristupljeno 13. 10. 2021.