2018 Winston-Salem Open
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| 2018 Winston-Salem Open | |
|---|---|
| Date | August 19–25 |
| Edition | 50th |
| Category | ATP World Tour 250 Series |
| Draw | 48S / 16D |
| Surface | Hard / outdoor |
| Location | Winston-Salem, North Carolina, U.S. |
| Venue | Wake Forest University |
| Champions | |
| Singles | |
 Daniil Medvedev | |
| Doubles | |
 Jean-Julien Rojer /  Horia Tecău | |
The 2018 Winston-Salem Open was a men's tennis tournament played on outdoor hard courts. It was the 50th edition of the Winston-Salem Open (as successor to previous tournaments in New Haven and Long Island), and part of the ATP World Tour 250 Series of the 2018 ATP World Tour. It took place at Wake Forest University in Winston-Salem, North Carolina, United States, from August 19 through August 25, 2018. It was the last event on the 2018 US Open Series before the 2018 US Open.
Singles main-draw entrants
Seeds
| Country | Player | Rank* | Seed |
|---|---|---|---|
 BEL |
|||
 ESP
|
Pablo Carreño Busta | 13 | 2 |
 GBR
|
Kyle Edmund | 16 | 3 |
 ITA
|
Marco Cecchinato | 22 | 4 |
 BIH |
|||
 KOR
|
Chung Hyeon | 25 | 6 |
 SRB
|
Filip Krajinović | 31 | 7 |
 USA
|
Steve Johnson | 33 | 8 |
| USA
|
Sam Querrey | 34 | 9 |
 GEO
|
Nikoloz Basilashvili | 36 | 10 |
| RUS
|
Andrey Rublev | 37 | 11 |
 FRA |
|||
| ESP
|
Albert Ramos Viñolas | 41 | 13 |
 CHI
|
Nicolás Jarry | 42 | 14 |
 AUS
|
Alex de Minaur | 43 | 15 |
 GER
|
Peter Gojowczyk | 47 | 16 |
* Rankings are as of August 13, 2018
Other entrants
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
Withdrawals
- Before the tournament
Alexandr Dolgopolov → replaced by 
Guido Pella
Jared Donaldson → replaced by 
Franko Škugor
Damir Džumhur → replaced by 
Dominik Köpfer
David Goffin → replaced by Guido Andreozzi
Mikhail Kukushkin → replaced by 
Laslo Đere
Feliciano López → replaced by 
Marcos Baghdatis- Fernando Verdasco → replaced by Jaume Munar
- During the tournament
Doubles main-draw entrants
Seeds
| Country | Player | Country | Player | Rank1 | Seed |
|---|---|---|---|---|---|
 POL
|
Łukasz Kubot |  BRA
|
Marcelo Melo | 23 | 1 |
| NED
|
Jean-Julien Rojer | ROU
|
Horia Tecău | 25 | 2 |
 JPN
|
Ben McLachlan | GER
|
Jan-Lennard Struff | 53 | 3 |
| CHI
|
Julio Peralta |  ARG
|
Horacio Zeballos | 64 | 4 |
- Rankings are as of August 13, 2018
Other entrants
The following pairs received wildcards into the doubles main draw:
The following pair received entry as alternates:
Withdrawals
- Before the tournament
Champions
Singles
Daniil Medvedev def. Steve Johnson, 6–4, 6–4
Doubles
Jean-Julien Rojer / 
Horia Tecău def. James Cerretani / 
Leander Paes, 6–4, 6–2