Clobenpropit
In today's world, Clobenpropit is a topic that sparks great interest and debate among people. Whether due to its relevance in society, its impact on history or its influence on culture, Clobenpropit is an aspect that cannot be overlooked. Over time, Clobenpropit has evolved and acquired new dimensions, which has generated greater interest from academics, specialists and the general public. In this article, we will explore the different facets of Clobenpropit, its importance and its impact on today's society.
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| Formula | C14H17ClN4S |
| Molar mass | 308.83 g·mol−1 |
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Clobenpropit is a histamine H3 receptor antagonist.[1] It has neuroprotective effects via stimulation of GABA release in brain cells in vitro.[2]
References
- ^ Sahlholm K, Nilsson J, Marcellino D, Fuxe K, Arhem P (2007). "The human histamine H3 receptor couples to GIRK channels in Xenopus oocytes". European Journal of Pharmacology. 567 (3): 206–210. doi:10.1016/j.ejphar.2007.04.032. PMID 17537431.
- ^ Dai H, Fu Q, Shen Y, Hu W, Zhang Z, Timmerman H, Leurs R, Chen Z (2007). "The histamine H3 receptor antagonist clobenpropit enhances GABA release to protect against NMDA-induced excitotoxicity through the cAMP/protein kinase A pathway in cultured cortical neurons". European Journal of Pharmacology. 563 (1–3): 117–123. doi:10.1016/j.ejphar.2007.01.069. PMID 17350613.
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