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Cyfluthrin

In today's world, Cyfluthrin is a constantly talked about topic that affects people of all ages and in all parts of the world. Its impact does not go unnoticed and its relevance is undeniable in various aspects of daily life. Both on a personal and professional level, Cyfluthrin has generated debate, has been the subject of study and has aroused the interest of numerous experts. Throughout history, Cyfluthrin has evolved and adapted to social, political and technological changes, significantly influencing the way we face the challenges of the present and the future. In this article, we will explore in depth the impact of Cyfluthrin and analyze its influence in different contexts, with the aim of better understanding its importance and the implications it has for today's society.

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Cyfluthrin
Names
Preferred IUPAC name
(R)-Cyano(4-fluoro-3-phenoxyphenyl)methyl (1R,3R)-3-(2,2-dichloroethen-1-yl)-2,2-dimethylcyclopropane-1-carboxylate
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.063.485 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C22H18Cl2FNO3/c1-22(2)15(11-19(23)24)20(22)21(27)29-18(12-26)13-8-9-16(25)17(10-13)28-14-6-4-3-5-7-14/h3-11,15,18,20H,1-2H3/t15-,18-,20-/m0/s1 checkY
    Key: QQODLKZGRKWIFG-QSFXBCCZSA-N checkY
  • InChI=1/C22H18Cl2FNO3/c1-22(2)15(11-19(23)24)20(22)21(27)29-18(12-26)13-8-9-16(25)17(10-13)28-14-6-4-3-5-7-14/h3-11,15,18,20H,1-2H3/t15-,18-,20-/m0/s1
    Key: QQODLKZGRKWIFG-QSFXBCCZBF
  • Cl/C(Cl)=C/3(C(=O)O(C#N)c2ccc(F)c(Oc1ccccc1)c2)C3(C)C
Properties
C22H18Cl2FNO3
Molar mass 434.29 g·mol−1
Melting point 60 °C (140 °F; 333 K)
2 μg/L
Pharmacology
P03BA01 (WHO) QP53AC12 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
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Cyfluthrin is a pyrethroid insecticide and common household pesticide. It is a complex organic compound and the commercial product is sold as a mixture of isomers. Like most pyrethroids (MoA 3a),[1] it is highly toxic to fish and invertebrates, but it is far less toxic to humans.[2] It is generally supplied as a 10–25% liquid concentrate for commercial use and is diluted prior to spraying onto agricultural crops and outbuildings.

Safety

In rats, the LD50s are 500, 800 (oral), and 600 (skin) mg/kg.[2]

Excessive exposure can cause nausea, headache, muscle weakness, salivation, shortness of breath and seizures. In humans, it is deactivated by enzymatic hydrolysis to several carboxylic acid metabolites, whose urinary excretion half-lives are in a range of 5–7 hours. Worker exposure to the chemical can be monitored by measurement of the urinary metabolites, while severe overdosage may be confirmed by quantification of cyfluthrin in blood or plasma.[3]

Health and safety risks are controlled by right to know laws that exist in most developed countries. Cyfluthrin is regulated in the US by the EPA.[4]

See also

References

  1. ^ "IRAC Mode of Action Classification Scheme Version 9.4". IRAC (Insecticide Resistance Action Committee) (pdf). March 2020.
  2. ^ a b Robert L. Metcalf (2002). "Insect Control". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a14_263. ISBN 9783527303854.
  3. ^ R. Baselt (2008). Disposition of Toxic Drugs and Chemicals in Man (8th ed.). Foster City, CA: Biomedical Publications. pp. 388–389.
  4. ^ "Pyrethroids and Pyrethrins". United States Environmental Protection Agency. Archived from the original on July 9, 2009.
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