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Lactofen

In today's world, Lactofen is a topic of great importance and interest to a large number of people. Since its emergence, Lactofen has captured the attention of millions of individuals around the world, generating debates, discussions and controversies in various fields. Its impact has been felt in society, politics, the economy, science and culture, among other aspects. As Lactofen continues to evolve and gain relevance on the global stage, it is essential to fully analyze and understand its influence and the implications it has on various aspects of daily life. In this article, we will explore in detail the different dimensions of Lactofen and its role in today's society.

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Lactofen[1]
Names
IUPAC name
Ethyl O--DL-lactate
Other names
2-Ethoxy-1-methyl-2-oxoethyl 5--2-nitrobenzoate
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.111.278 Edit this at Wikidata
UNII
  • InChI=1S/C19H15ClF3NO7/c1-3-29-17(25)10(2)30-18(26)13-9-12(5-6-15(13)24(27)28)31-16-7-4-11(8-14(16)20)19(21,22)23/h4-10H,3H2,1-2H3 ☒N
    Key: CONWAEURSVPLRM-UHFFFAOYSA-N ☒N
  • InChI=1/C19H15ClF3NO7/c1-3-29-17(25)10(2)30-18(26)13-9-12(5-6-15(13)24(27)28)31-16-7-4-11(8-14(16)20)19(21,22)23/h4-10H,3H2,1-2H3
    Key: CONWAEURSVPLRM-UHFFFAOYAB
  • CCOC(=O)C(C)OC(=O)c1cc(ccc1(=O))Oc2ccc(cc2Cl)C(F)(F)F
Properties
C19H15ClF3NO7
Molar mass 461.77 g·mol−1
Appearance White crystalline solid
Melting point 43.9 to 45.5 °C (111.0 to 113.9 °F; 317.0 to 318.6 K)
0.1 mg/L @ 20 degrees C
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
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Lactofen is a complex ester of acifluorfen and is a nitrophenyl ether selective herbicide[2][3] and fungicide.[4][5][6] It is used in postemergence applications to certain crops which are resistant to its action.[2] The name "Lactofen" is approved by the American National Standards Institute and the Weed Science Society of America, and is also approved in China (乳氟禾草灵).

Lactofen is applied as a foliar spray and is commonly used to control broadleaved weeds in soybeans, cereals, potatoes and peanuts. It may be combined with oil or fertilizer adjuvants and surfactants. Some formulations include solvents such as xylenes and cumene.[1] It is also used as a fungicide for Sclerotinia white moulds on soybean.[4][5][6]

Lactofen is available in solid form or as an emulsifiable concentrate under the trade name COBRA.[1]

Toxicology

Lactofen is slightly non-toxic to humans when ingested or inhaled. It can cause skin irritation including reddening, swelling and possibly corrosive burns. It is a severe eye irritant and can cause permanent damage to the eyes when there is sufficient exposure.[7]

It was found to be practically non-toxic to the species of birds that were studied.[8] Toxicity to fish and other aquatic organisms varied and it was eliminated in fish within fourteen days. It is of low toxicity to bees.[9]

Lactofen has a very low solubility in water and is not expected to contaminate surface waters. It binds tightly to soil and is then broken down in between one and seven days.[8][10]

References

  1. ^ a b c EXTOXNET: Extension Toxicology Network
  2. ^ a b Herbicide Mode-of-Action Summary
  3. ^ SDSU Extension. 2019 South Dakota Pest Management Guide - Soybeans - A guide to managing weeds, insects, and diseases (PDF).
  4. ^ a b "White Mold in Soybeans - Crops". NDSU Agriculture and Extension. 17 June 2021. Retrieved 2021-07-29.
  5. ^ a b "Applying foliar fungicides for control of white mold in soybeans". Michigan State University Extension. 18 June 2012. Retrieved 2021-07-29.
  6. ^ a b Kichler, Jeremy (2021-07-19). "Questions of the Week!! 7/19/21 - Colquitt County Ag Report". University of Georgia Extension. Retrieved 2021-07-29.
  7. ^ Valent USA. 1993. Material Safety Data Sheet for Valent Cobra Herbicide. Valent USA Corporation. Walnut Creek, CA.
  8. ^ a b Herbicide Handbook of the Weed Science Society of America. 1989. Sixth edition. Champaign, IL
  9. ^ US Environmental Protection Agency. 1995. File: Lactofen, Integrated Risk Information System (IRIS). National Library of Medicine "Toxline" Database, 4/95.
  10. ^ US Environmental Protection Agency. 1987. Fact Sheet Number 128: Lactofen. Washington, DC.
  • Lactofen in the Pesticide Properties DataBase (PPDB)