Piperocaine

In today's world, Piperocaine is a topic of great relevance and interest to a wide spectrum of people. From professionals to amateurs, Piperocaine has captured the attention of millions around the world. Whether due to its impact on society, its relevance in the scientific field or its influence on popular culture, Piperocaine has become a recurring topic in daily conversations, academic debates and the media. In this article, we will explore in depth the different aspects related to Piperocaine, analyzing its importance, its implications and its evolution over time. Join us on this journey to discover more about Piperocaine and its impact on the world today!

Chemical compound

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Pharmaceutical compound

Piperocaine

Clinical data
ATC code	none
Identifiers
IUPAC name 3-(2-Methylpiperidin-1-yl)propyl benzoate
CAS Number	136-82-3 Y
PubChem CID	10782
ChemSpider	10326 N
UNII	F66XUI6GZL
ChEMBL	ChEMBL127865 N
CompTox Dashboard (EPA)	DTXSID8048315
ECHA InfoCard	100.004.784
Chemical and physical data
Formula	C16H23NO2
Molar mass	261.365 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1CCCCN1CCCOC(C2=CC=CC=C2)=O
InChI InChI=1S/C16H23NO2/c1-14-8-5-6-11-17(14)12-7-13-19-16(18)15-9-3-2-4-10-15/h2-4,9-10,14H,5-8,11-13H2,1H3 N Key:YQKAVWCGQQXBGW-UHFFFAOYSA-N N
NY (what is this?)  (verify)

Piperocaine is a local anesthetic drug developed in the 1920s and used as its hydrochloride salt for infiltration and nerve blocks.

Synthesis

Alkylation between 3-chloropropyl benzoate (1) and Pipicoline (2) provides piperocaine (3).

See also

• Hexylcaine

References

1. ^ McElvain, S. M. (1927). "PIPERIDINE DERIVATIVES IV. SUBSTITUTED PIPERIDINE-ALKYL BENZOATES AND PARA-AMINOBENZOATES". Journal of the American Chemical Society 49 (11): 2835–2840. doi:10.1021/ja01410a030.
2. ^ Samuel M Mcelvain, U.S. patent 1,784,903 (1930).

Further reading

• Tiedt TN, Albuquerque EX, Bakry NM, Eldefrawi ME, Eldefrawi AT (November 1979). "Voltage- and time-dependent actions of piperocaine on the ion channel of the acetylcholine receptor". Molecular Pharmacology. 16 (3): 909–21. doi:10.1016/S0026-895X(25)13832-7. PMID 316855.^[1]</ref>

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1. ^ Costich, Emmett R. (1950-02-01). "A Preliminary Study of the Efficiency of Piperocaine Hydrochloride as a Local Anesthetic in Dental Surgery". The Journal of the American Dental Association. 40 (2): 163–169. doi:10.14219/jada.archive.1950.0022. ISSN 0002-8177. PMID 15402120.