RPS6KC1

In this article, we will explore the impact that RPS6KC1 has had on contemporary society. RPS6KC1 has become a topic of growing interest in recent years, since its influence covers different areas of daily life. Since its emergence, RPS6KC1 has generated debate and controversy, as well as driving significant changes in the way people perceive and experience the world around them. Throughout these pages, we will analyze the various facets of RPS6KC1, examining its implications on culture, politics, technology, economics, and people's personal lives. Using a multidisciplinary approach, this article seeks to shed light on the profound impact RPS6KC1 has had on modern society.

Enzyme found in humans

RPS6KC1
Identifiers
Aliases	RPS6KC1, RPK118, RSKL1, S6K-delta-1, S6PKh1, humS6PKh1, ribosomal protein S6 kinase C1
External IDs	OMIM: 617517; MGI: 2443419; HomoloGene: 8244; GeneCards: RPS6KC1; OMA:RPS6KC1 - orthologs
Gene location (Mouse) Chr. Chromosome 1 (mouse)[1] Band 1|1 H6 Start 190,432,399 bp[1] End 190,643,967 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) n/a Top expressed in dentate gyrus of hippocampal formation granule cell supraoptic nucleus granulocyte neural layer of retina muscle of thigh stroma of bone marrow otic vesicle cingulate gyrus saccule yolk sac BioGPS More reference expression data
Gene ontology Molecular function transferase activity nucleotide binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding phosphatidylinositol binding kinase activity lipid binding Cellular component membrane cytoplasm endosome early endosome Biological process protein phosphorylation signal transduction phosphorylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26750 320119 Ensembl ENSG00000136643 ENSMUSG00000089872 UniProt Q96S38 Q8BLK9 RefSeq (mRNA) NM_001136138 NM_001287218 NM_001287219 NM_001287220 NM_001287221 NM_012424 NM_178775 RefSeq (protein) NP_001129610 NP_001274147 NP_001274148 NP_001274149 NP_001274150 NP_036556 NP_001336575 NP_001336576 NP_001336577 NP_001336578 NP_001336579 NP_001336580 NP_001336581 NP_001336582 NP_001336583 NP_001336586 NP_001336587 NP_001336588 NP_001336589 NP_001336590 NP_001336591 NP_001336592 NP_001336593 NP_001336594 NP_001336595 NP_001336596 NP_001336597 NP_001336598 NP_001336599 NP_001336600 NP_001336601 NP_848890 Location (UCSC) n/a Chr 1: 190.43 – 190.64 Mb PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Ribosomal protein S6 kinase delta-1 is an enzyme that in humans is encoded by the RPS6KC1 gene.^[4][5]

References

1. ^ ^{a b c} GRCm38: Ensembl release 89: ENSMUSG00000089872 – Ensembl, May 2017
2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ Zhang H, Yu L, Mao N, Fu Q, Tu Q, Gao J, Zhao S (Feb 2000). "Cloning, characterization, and chromosome mapping of RPS6KC1, a novel putative member of the ribosome protein S6 kinase family, to chromosome 12q12-q13.1". Genomics. 61 (3): 314–8. doi:10.1006/geno.1999.5963. PMID 10552933.
5. ^ "Entrez Gene: RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1".

Further reading

• Hayashi S, Okada T, Igarashi N, Fujita T, Jahangeer S, Nakamura S (2002). "Identification and characterization of RPK118, a novel sphingosine kinase-1-binding protein". J. Biol. Chem. 277 (36): 33319–24. doi:10.1074/jbc.M201442200. hdl:20.500.14094/D1002671. PMID 12077123.
• Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Lehner B, Semple JI, Brown SE, Counsell D, Campbell R, Sanderson CM (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. 83 (1): 153–67. doi:10.1016/S0888-7543(03)00235-0. PMID 14667819.
• Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R, Wakamatsu A, Hayashi K, Sato H (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Liu L, Yang C, Yuan J, Chen X, Xu J, Wei Y, Yang J, Lin G, Yu L (2005). "RPK118, a PX domain-containing protein, interacts with peroxiredoxin-3 through pseudo-kinase domains". Mol. Cells. 19 (1): 39–45. doi:10.1016/S1016-8478(23)13134-7. PMID 15750338.
• Gregory SG, Barlow KF, McLay KE, Kaul R, Swarbreck D, Dunham A, Scott CE, Howe KL, Woodfine K (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

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