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Trepipam

In today's world, Trepipam is a relevant topic and of great interest to a wide spectrum of people. From its impact on society to its implications on daily life, Trepipam is an issue that deserves attention and in-depth analysis. Whether it is a recent event, a public figure or a global phenomenon, Trepipam continues to generate debate and interest in different areas. In this article, we will explore different aspects and perspectives related to Trepipam, with the aim of expanding understanding and reflection on its importance in our current reality.

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Trepipam
Clinical data
Other namesSCH-12679; SCH12679
Identifiers
  • (5R)-7,8-dimethoxy-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepine
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC19H23NO2
Molar mass297.398 g·mol−1
3D model (JSmol)
Specific rotation+31.8°
Density1.072 ± 0.06 g/cm3 (predicted)
Melting point105–106 °C (221–223 °F) (experimental)
Boiling point416.8 ± 45.0 °C (782.2 ± 81.0 °F) (predicted)
  • CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)OC)OC
  • InChI=1S/C19H23NO2/c1-20-10-9-15-11-18(21-2)19(22-3)12-16(15)17(13-20)14-7-5-4-6-8-14/h4-8,11-12,17H,9-10,13H2,1-3H3/t17-/m1/s1
  • Key:ICPHJSKVAZMKIV-QGZVFWFLSA-N

Trepipam (INNTooltip International Nonproprietary Name; developmental code name SCH-12679) is a dopamine receptor agonist of the benzazepine group that was never marketed.[1] It acts specifically as an agonist of the dopamine D1 receptor.[2] It is closed related structurally to fenoldopam, a peripherally acting selective D1 receptor partial agonist which is used as an antihypertensive agent.

See also

References

  1. ^ Lednicer D (4 March 2009). Strategies for Organic Drug Synthesis and Design. John Wiley & Sons. pp. 495–. ISBN 978-0-470-39959-0.
  2. ^ Goode-Romero G, Winnberg U, Domínguez L, Ibarra IA, Vargas R, Winnberg E, Martínez A (December 2020). "New information of dopaminergic agents based on quantum chemistry calculations". Sci Rep. 10 (1) 21581. Bibcode:2020NatSR..1021581G. doi:10.1038/s41598-020-78446-4. PMC 7725812. PMID 33299000.