Tovetumab

In today's world, Tovetumab has become a topic of great interest to a wide range of people. From scientists and experts in the field to the general public, Tovetumab has captured the attention of many due to its relevance and impact on modern society. In order to better understand this phenomenon, it is crucial to explore the different perspectives and opinions that exist on the matter. In this article, we will delve into the fascinating world of Tovetumab, analyzing its importance, its evolution over time and its influence on various aspects of daily life. From its origin to its relevance today, we will discover how Tovetumab has left its mark on the world and continues to be a topic of debate and analysis today.

Tovetumab
Monoclonal antibody
Type?
SourceHuman
TargetPDGFRA
Clinical data
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
KEGG
Chemical and physical data
FormulaC6400H9906N1726O2002S54
Molar mass144792.97 g·mol−1

Tovetumab is an anti-PDGFRa monoclonal antibody designed for the treatment of cancer. It was developed by MedImmune, and trialed for use in glioblastoma and non-small cell lung cancer. Development was discontinued in 2013.

This drug was developed by MedImmune, LLC.[citation needed]

References

  1. ^ Statement On A Nonproprietary Name Adopted By The USAN Council - Tovetumab, American Medical Association.
  2. ^ Liang M, Wang B, Schneider A, Vainshtein I, Roskos L (November 2020). "A Novel Pharmacodynamic Biomarker and Mechanistic Modeling Facilitate the Development of Tovetumab, a Monoclonal Antibody Directed Against Platelet-Derived Growth Factor Receptor Alpha, for Cancer Therapy". The AAPS Journal. 23 (1): 4. doi:10.1208/s12248-020-00523-3. PMID 33210183. S2CID 227067803.
  3. ^ "Tovetumab". AdisInsight. Springer Nature Switzerland AG.
  4. ^ Williams R (January 2015). "Discontinued in 2013: oncology drugs". Expert Opinion on Investigational Drugs. 24 (1): 95–110. doi:10.1517/13543784.2015.971154. PMID 25315907. S2CID 23390614.