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U-92016-A

In this article, we are going to address the topic of U-92016-A, which has captured the attention of many in recent times. U-92016-A is a topic that has generated controversy and debate, arousing great interest both in the academic community and in society in general. Throughout this article, we will explore the different aspects related to U-92016-A, from its origin and evolution, to its impact in different areas. Additionally, we will analyze the possible implications and consequences that U-92016-A may have in the future. Without a doubt, U-92016-A is a topic that deserves deep reflection and analysis, so it is crucial to increase our understanding of it.

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U-92016-A
Identifiers
  • (8R)-8-(Dipropylamino)-6,7,8,9-tetrahydro-3H-benzindole-2-carbonitrile
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC19H25N3
Molar mass295.430 g·mol−1
3D model (JSmol)
  • N#Cc3cc1c(ccc2c1C(N(CCC)CCC)CC2)3
  • InChI=1S/C19H25N3/c1-3-9-22(10-4-2)16-7-5-14-6-8-19-18(17(14)12-16)11-15(13-20)21-19/h6,8,11,16,21H,3-5,7,9-10,12H2,1-2H3/t16-/m1/s1 checkY
  • Key:WDDZPZKGLZNGEH-MRXNPFEDSA-N checkY
  (verify)

U-92,016-A is a psychoactive drug and research chemical used in scientific studies. It acts as a potent, high efficacy, and selective 5-HT1A receptor full agonist with a long duration of action.[1][2] It has been suggested that it could be developed as an anxiolytic or antidepressant drug.[1]

References

  1. ^ a b Romero AG, Leiby JA, McCall RB, Piercey MF, Smith MW, Han F (1993). "Novel 2-substituted tetrahydro-3H-benzindolamines: highly potent and selective agonists acting at the 5-HT1A receptor as possible anxiolytics and antidepressants". J Med Chem. 36 (15): 2066–2074. doi:10.1021/jm00067a003. PMID 8101876.
  2. ^ McCall RB, Romero AG, Bienkowski MJ, Harris DW, McGuire JC, Piercey MF, Shuck ME, Smith MW, Svensson KA, Schreur PJ, et al. (1994). "Characterization of U-92016A as a selective, orally active, high intrinsic activity 5-hydroxytryptamine1A agonist". J Pharmacol Exp Ther. 271 (2): 875–883. doi:10.1016/S0022-3565(25)23851-4. PMID 7965808.


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