Nipecotic acid
Nowadays, Nipecotic acid has become a topic of great interest and relevance in today's society. Whether on a personal, professional or academic level, Nipecotic acid has aroused the interest of many people due to its impact and repercussion in different areas of daily life. This is why it is essential to analyze and understand all aspects related to Nipecotic acid, from its origins to its short- and long-term consequences. In this article, we will delve into the fascinating world of Nipecotic acid, exploring its many facets and unraveling its mysteries to obtain a more complete and in-depth view of this phenomenon.
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| ECHA InfoCard | 100.007.159 |
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| Formula | C6H11NO2 |
| Molar mass | 129.159 g·mol−1 |
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Nipecotic acid is a GABA uptake inhibitor used in scientific research.
See also
References
- ^ Macdonald, R.L. (2012). Eadie, Mervyn J.; Vajda, Frank J. E. (eds.). Antiepileptic drugs: pharmacology and therapeutics (First ed.). : Springer. p. 130. ISBN 978-3-642-64244-9.
In contrast, prolonged (1 h) exposure to gabapentin enhanced the shunting effect on CAl region excitatory postsynaptic potentials induced by the GABA uptake inhibitor, nipecotic acid, which promotes GABA release.
- ^ Takahashi K, Miyoshi S, Kaneko A, Copenhagen DR (1995). "Actions of nipecotic acid and SKF89976A on GABA transporter in cone-driven horizontal cells dissociated from the catfish retina". Jpn. J. Physiol. 45 (3): 457–73. doi:10.2170/jjphysiol.45.457. PMID 7474528.
- ^ Wahab A, Heinemann U, Albus K (October 2009). "Effects of gamma-aminobutyric acid (GABA) agonists and a GABA uptake inhibitor on pharmacoresistant seizure like events in organotypic hippocampal slice cultures". Epilepsy Research. 86 (2–3): 113–23. doi:10.1016/j.eplepsyres.2009.05.008. PMID 19535226. S2CID 32999271.
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