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C-8813

In today's world, C-8813 has become a topic of utmost importance and relevance. Whether in the personal, professional, political or social sphere, C-8813 has gained great relevance and has generated a wide debate among experts and society in general. The importance of C-8813 lies in its direct impact on different aspects of daily life, as well as its influence on the development and evolution of different areas of knowledge and culture. This is why it is essential to analyze and understand in depth the importance and impact that C-8813 has on our current reality, as well as to anticipate possible future scenarios that may arise as a result of its presence in various areas.

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C-8813
Identifiers
  • trans-4-(p-Bromophenyl)-4-(dimethylamino)-1-(2-(thiophen-2-yl)ethyl)cyclohexanol
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC20H26BrNOS
Molar mass408.40 g·mol−1
3D model (JSmol)
  • BrC1=CC=C(2(CC(CC2)(CCC3=CC=CS3)O)N(C)C)C=C1
  • InChI=1S/C20H26BrNOS/c1-22(2)20(16-5-7-17(21)8-6-16)13-11-19(23,12-14-20)10-9-18-4-3-15-24-18/h3-8,15,23H,9-14H2,1-2H3/t19-,20- ☒N
  • Key:XRDNIYBVNZLPJE-MXVIHJGJSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

C-8813 (thiobromadol) is a potent μ-opioid receptor agonist with a distinctive chemical structure which is not closely related to other established families of opioid drugs. The trans-isomer was found to be around 591 times more potent than morphine in animal studies.[1] The same study assigned a potency of 504 times that of morphine to the related compound BDPC.

C-8813 is claimed to be similarly potent at the δ-opioid receptor, which antagonizes the μ-induced depression of breathing, presumably making the drug safer.[1]

C-8813 has never been approved for use in humans.[citation needed]

See also

References

  1. ^ a b Liu ZH, Jin WQ, Dai QY, Chen XJ, Zhang HP, Chi ZQ (May 2003). "Opioid activity of C8813, a novel and potent opioid analgesic". Life Sciences. 73 (2): 233–41. doi:10.1016/S0024-3205(03)00263-7. PMID 12738037.
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