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Nicodicodine

In this article we are going to delve deeper into Nicodicodine and explore its different facets. Nicodicodine is an exciting topic that has captured the attention of many people over the years. From its impact on society to its implications on everyday life, Nicodicodine is a topic that continues to generate interest and debate. Throughout this article, we will take a closer look at Nicodicodine and discuss its relevance in various contexts. Additionally, we will explore the latest research and discoveries related to Nicodicodine, in order to shed light on this fascinating topic. Without a doubt, Nicodicodine is a topic worthy of attention and reflection, and this article seeks to offer a broad and complete look at it. Get ready to enter the world of Nicodicodine and discover everything it has to offer.

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Nicodicodine
Structural formula
Ball-and-stick model
Clinical data
Other namesNicodicodeine, 6-Nicotinoyldihydrocodeine, Nicodicodina,[1] Nicodicodinum[1]
Routes of
administration		Oral, intravenous
ATC code
  • none
Legal status
Legal status
Identifiers
  • (5alpha,6alpha)-3-Methoxy-17-methyl-4,5-epoxymorphinan-6-yl pyridine-3-carboxylate[7]
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.011.241 Edit this at Wikidata
Chemical and physical data
FormulaC24H26N2O4
Molar mass406.482 g·mol−1
3D model (JSmol)
  • CN1CCC23C4C1CC5=C2C(=C(C=C5)OC)OC3C(CC4)OC(=O)C6=CN=CC=C6
  • InChI=InChI=1S/C24H26N2O4/c1-26-11-9-24-16-6-8-19(29-23(27)15-4-3-10-25-13-15)22(24)30-21-18(28-2)7-5-14(20(21)24)12-17(16)26/h3-5,7,10,13,16-17,19,22H,6,8-9,11-12H2,1-2H3/t16-,17+,19-,22-,24-/m0/s1
  • Key:GTGRMWCOZHEYRL-MJFIPZRTSA-N
 ☒NcheckY (what is this?)  (verify)

Nicodicodine is an opioid developed as a cough suppressant and analgesic.[8] Synthesized in 1904, it is not commonly used, but has activity similar to other opioids.[8] Nicodicodine is metabolised in the liver by demethylation to produce 6-nicotinoyldihydromorphine, and subsequently further metabolised to dihydromorphine. Since the final active metabolite is the slightly stronger opiate dihydromorphine rather than morphine, nicodicodine can be expected to be marginally more potent and longer acting than nicocodeine. Side effects are similar to those of other opioids and include itching, nausea and respiratory depression.

References

  1. ^ a b "Nicodicodine [INN:BAN:DCF] | SIELC". www.sielc.com. 16 May 2018. Retrieved 12 January 2019.
  2. ^ "Drugs Misuse Regulation 1987". www.legislation.qld.gov.au. Office of the Queensland Parliamentary Counsel. Retrieved 10 January 2019.
  3. ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-03.
  4. ^ "Misuse of Drugs Act 1971". www.legislation.gov.uk. Retrieved 10 January 2019.
  5. ^ "The International Drug Control Conventions". undocs.org. United Nations. Retrieved 10 January 2019.
  6. ^ "Anlage II BtMG - Einzelnorm". www.gesetze-im-internet.de.
  7. ^ "Chemistry Dashboard". comptox.epa.gov. U.S. Environmental Protection Agency. Archived from the original on January 11, 2019. Retrieved 10 January 2019.
  8. ^ a b Stolberg VB (2016). Painkillers: History, Science, and Issues. ABC-CLIO. p. 110. ISBN 978-1-4408-3532-2. Retrieved 12 January 2019.


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