Evoxine

In today's world, Evoxine is a topic that has become increasingly relevant. Both on a personal and professional level, Evoxine has captured the attention of a large number of individuals and has generated debate in different sectors. Over time, opinions and perspectives on Evoxine have evolved, resulting in a growing interest in fully understanding its importance and impact on society. In this article, we will explore in detail the various facets of Evoxine, analyzing its impact in different contexts and offering a comprehensive vision that allows us to fully understand its relevance in today's world.

Evoxine
Names
IUPAC name
(±)-1-(4,8-Dimethoxyfuroquinolin-7-yl)oxy-3-methylbutane-2,3-diol
Other names
Haploperine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C18H21NO6/c1-18(2,21)13(20)9-25-12-6-5-10-14(16(12)23-4)19-17-11(7-8-24-17)15(10)22-3/h5-8,13,20-21H,9H2,1-4H3
    Key: FGANMDNHTVJAHL-UHFFFAOYSA-N
  • InChI=1/C18H21NO6/c1-18(2,21)13(20)9-25-12-6-5-10-14(16(12)23-4)19-17-11(7-8-24-17)15(10)22-3/h5-8,13,20-21H,9H2,1-4H3
    Key: FGANMDNHTVJAHL-UHFFFAOYAV
  • CC(C)(C(COC1=C(C2=C(C=C1)C(=C3C=COC3=N2)OC)OC)O)O
Properties
C18H21NO6
Molar mass 347.367 g·mol−1
Pharmacology
none
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
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Evoxine (haploperine) is a furoquinoline alkaloid with hypnotic and sedative effects. It is found naturally in a variety of Australian and African plants including Evodia xanthoxyloides and Teclea gerrardii.

References

  1. ^ Eastwood, FW; Hughes, GK; Ritchie, E. (1954). "Alkaloids of the Australian Rutaceae: Evodia xanthoxyloides F.Muell. IV. The structures of Evoxine and Evoxoidine". Australian Journal of Chemistry. 7 (1): 87–98. doi:10.1071/CH9540087.
  2. ^ Waffo, AF; Coombes, PH; Crouch, NR; Mulholland, DA; El Amin, SM; Smith, PJ (2007). "Acridone and furoquinoline alkaloids from Teclea gerrardii (Rutaceae: Toddalioideae) of southern Africa". Phytochemistry. 68 (5): 663–7. Bibcode:2007PChem..68..663K. doi:10.1016/j.phytochem.2006.10.011. PMID 17174364.