Acecarbromal

In today's world, Acecarbromal has become a relevant topic for a wide spectrum of society. Since its appearance, Acecarbromal has caused a great impact in different areas, generating discussions, debates and conflicting opinions. Its influence has crossed borders and has aroused the interest of experts on the subject, as well as the population in general. Given its relevance, it is important to analyze in detail and objectively all aspects related to Acecarbromal, understanding its implications, consequences and possible solutions. In this article, we will thoroughly explore the phenomenon of Acecarbromal, from its origins to its current situation, with the aim of providing a complete and enriching perspective on this topic of global interest.

Acecarbromal
Seletal formula of acebromal
Names
Preferred IUPAC name
N-(Acetylcarbamoyl)-2-bromo-2-ethylbutanamide
Other names
1-Acetyl-3-(2-bromo-2-ethylbutyryl)urea
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.000.953 Edit this at Wikidata
EC Number
  • 201-047-1
KEGG
MeSH acecarbromal
UNII
  • InChI=1S/C9H15BrN2O3/c1-4-9(10,5-2)7(14)12-8(15)11-6(3)13/h4-5H2,1-3H3,(H2,11,12,13,14,15) checkY
    Key: SAZUGELZHZOXHB-UHFFFAOYSA-N checkY
  • CCC(Br)(CC)C(=O)NC(=O)NC(C)=O
Properties
C9H15BrN2O3
Molar mass 279.134 g·mol−1
Pharmacology
Oral
Legal status
  • In general: ℞ (Prescription only)
Related compounds
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).

Acecarbromal (INN) (brand names Sedamyl, Abasin, Carbased, Paxarel, Sedacetyl, numerous others), also known as acetylcarbromal and acetyladalin, is a hypnotic and sedative drug of the ureide (acylurea) group discovered by Bayer in 1917 that was formerly marketed in the United States and Europe. It is also used in combination with extract of quebracho and vitamin E as a treatment for erectile dysfunction under the brand name Afrodor in Europe. Acecarbromal is structurally related to the barbiturates, which are basically cyclized ureas. Prolonged use is not recommended as it can cause bromine poisoning.

See also

References

  1. ^ DE 327129, "Verfahren zur Darstellung von Derivaten bromacylierter Harnstoffe (Procedures for the preparation of derivatives of bromoacylated urea)", issued 5 October 1920, assigned to Bayer AG 
  2. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 2–. ISBN 978-1-4757-2085-3.
  3. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 4–. ISBN 978-3-88763-075-1.
  4. ^ Muller NF, Dessing RP, eds. (19 June 1998). European Drug Index: European Drug Registrations, Fourth Edition. CRC Press. pp. 36–. ISBN 978-3-7692-2114-5.
  5. ^ Baumbusch F, Papp GK, Kopa ZS (1995). "Treatment for potency problems with Afrodor 2000". Acta Chirurgica Hungarica. 35 (1–2): 87–92. PMID 8659243.
  6. ^ Sperling H, Lümmen G, Luboldt HJ, Rübben H (January 1999). "". Der Urologe. Ausg. A. 38 (1): 56–9. doi:10.1007/s001200050246. PMID 10081103. S2CID 24907635.
  7. ^ a b Williams DA, Foye WO, Lemke TL (January 2002). Foye's Principles of Medicinal Chemistry. Lippincott Williams & Wilkins. pp. 380–. ISBN 978-0-683-30737-5.