Core binding factor

In this article we want to address the topic of Core binding factor in depth, analyzing its implications from different perspectives and offering a complete overview of the issue. Core binding factor is a topic of utmost importance today, as it has a significant impact on various aspects of society. Throughout these pages, we will explore its origin, evolution, implications and possible solutions, with the aim of providing the reader with a broad and detailed overview of Core binding factor. Through a comprehensive and rigorous approach, we hope to contribute to the understanding and reflection on this topic that is so relevant today.

Type of transcription factor

The Core binding factor (CBF) is a group of heterodimeric transcription factors.

Core binding factors are composed of:

• a non-DNA-binding CBFβ chain (CBFB)
• a DNA-binding CBFα chain (RUNX1, RUNX2, RUNX3)

References

• de Bruijn M, Speck N (2004). "Core-binding factors in hematopoiesis and immune function". Oncogene. 23 (24): 4238–48. doi:10.1038/sj.onc.1207763. PMID 15156179.

See also

• AI-10-49, an anti-leukemic drug under development.

External links

• Core+Binding+Factors at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

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