ZNF19

In this article, we will explore the impact that ZNF19 has had on different aspects of modern society. From his influence on the economy to his role in popular culture, ZNF19 has left a deep mark on our world. We will analyze its evolution over time and the significant changes it has produced in various areas. Furthermore, we will examine the debates and controversies it has generated, as well as the possible future implications of its presence. Through a multidisciplinary approach, this article seeks to provide a broader and deeper understanding of ZNF19 and its relevance today.

Protein-coding gene in the species Homo sapiens

ZNF19
Identifiers
Aliases	ZNF19, KOX12, zinc finger protein 19
External IDs	OMIM: 194525; HomoloGene: 56009; GeneCards: ZNF19; OMA:ZNF19 - orthologs
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16q22.2 Start 71,464,555 bp[1] End 71,565,089 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube mucosa of ileum pancreatic ductal cell tibialis anterior muscle right testis left testis gonad anterior pituitary right lobe of thyroid gland left lobe of thyroid gland n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA-binding transcription factor activity DNA binding metal ion binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component intracellular anatomical structure nucleus Biological process regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7567 n/a Ensembl ENSG00000157429 n/a UniProt P17023 n/a RefSeq (mRNA) NM_006961 NM_152907 n/a RefSeq (protein) NP_008892 n/a Location (UCSC) Chr 16: 71.46 – 71.57 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Zinc finger protein 19 is a protein that in humans is encoded by the ZNF19 gene.^[3][4][5]

The protein encoded by this gene contains a zinc finger, a nucleic acid-binding domain present in many transcription factors. This gene is located in a region next to ZNF23, a gene also encoding a zinc finger protein, on chromosome 16.^[5]

References

1. ^ ^{a b c} GRCh38: Ensembl release 89: ENSG00000157429 – Ensembl, May 2017
2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. ^ Lichter P, Bray P, Ried T, Dawid IB, Ward DC (Sep 1992). "Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes". Genomics. 13 (4): 999–1007. doi:10.1016/0888-7543(92)90013-I. PMID 1505991.
4. ^ Bray P, Lichter P, Thiesen HJ, Ward DC, Dawid IB (Dec 1991). "Characterization and mapping of human genes encoding zinc finger proteins". Proc Natl Acad Sci U S A. 88 (21): 9563–7. Bibcode:1991PNAS...88.9563B. doi:10.1073/pnas.88.21.9563. PMC 52758. PMID 1946370.
5. ^ ^{a b} "Entrez Gene: ZNF19 zinc finger protein 19".

Further reading

• Thiesen HJ (1991). "Multiple genes encoding zinc finger domains are expressed in human T cells". New Biol. 2 (4): 363–74. PMID 2288909.
• Tommerup N, Vissing H (1995). "Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders". Genomics. 27 (2): 259–64. doi:10.1006/geno.1995.1040. PMID 7557990.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

External links

• ZNF19+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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