ZNF22

In today's world, ZNF22 is a widely discussed topic that has gained relevance in different areas of society. From its impact on the economy to its influence on interpersonal relationships, ZNF22 has generated endless debates and reflections. As time has progressed, opinions and perspectives on ZNF22 have evolved, giving rise to a wide range of approaches and analyzes on the matter. In this article, we will explore the different dimensions of ZNF22 and analyze its importance in the current context, with the aim of providing a comprehensive vision of this very relevant topic.

Protein-coding gene in the species Homo sapiens

ZNF22
Identifiers
Aliases	ZNF22, HKR-T1, KOX15, ZNF422, Zfp422, zinc finger protein 22
External IDs	OMIM: 194529; MGI: 1914505; HomoloGene: 5067; GeneCards: ZNF22; OMA:ZNF22 - orthologs
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q11.21 Start 45,000,923 bp[1] End 45,005,326 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 E3 Start 116,600,977 bp[2] End 116,605,960 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone ganglionic eminence secondary oocyte islet of Langerhans body of pancreas endometrium lymph node Achilles tendon trabecular bone tibia Top expressed in ventricular zone ganglionic eminence genital tubercle tail of embryo neural tube mesencephalon thymus epiblast serous sac stomach More reference expression data BioGPS More reference expression data
Gene ontology Molecular function zinc ion binding metal ion binding DNA binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus nucleoplasm Biological process odontogenesis regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7570 67255 Ensembl ENSG00000165512 ENSMUSG00000059878 UniProt P17026 Q9ERU3 RefSeq (mRNA) NM_006963 NM_026057 NM_001302439 NM_001302440 RefSeq (protein) NP_008894 NP_008894.2 NP_001289368 NP_001289369 NP_080333 Location (UCSC) Chr 10: 45 – 45.01 Mb Chr 6: 116.6 – 116.61 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Zinc finger protein 22 is a protein that in humans is encoded by the ZNF22 gene.^[5]

References

1. ^ ^{a b c} GRCh38: Ensembl release 89: ENSG00000165512 – Ensembl, May 2017
2. ^ ^{a b c} GRCm38: Ensembl release 89: ENSMUSG00000059878 – Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ "Entrez Gene: ZNF22 zinc finger protein 22 (KOX 15)".

Further reading

• Wu BY, Hanley EW, Turka LA, Nabel GJ (1992). "Isolation of a cDNA clone encoding a zinc finger protein highly expressed in T-leukemia lines". Blood. 80 (10): 2571–6. doi:10.1182/blood.V80.10.2571.2571. PMID 1421376.
• Lichter P, Bray P, Ried T, et al. (1992). "Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes". Genomics. 13 (4): 999–1007. doi:10.1016/0888-7543(92)90013-I. PMID 1505991.
• Rousseau-Merck MF, Tunnacliffe A, Berger R, et al. (1992). "A cluster of expressed zinc finger protein genes in the pericentromeric region of human chromosome 10". Genomics. 13 (3): 845–8. doi:10.1016/0888-7543(92)90166-P. PMID 1639412.
• Bray P, Lichter P, Thiesen HJ, et al. (1991). "Characterization and mapping of human genes encoding zinc finger proteins". Proc. Natl. Acad. Sci. U.S.A. 88 (21): 9563–7. Bibcode:1991PNAS...88.9563B. doi:10.1073/pnas.88.21.9563. PMC 52758. PMID 1946370.
• Huebner K, Druck T, Croce CM, Thiesen HJ (1991). "Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering". Am. J. Hum. Genet. 48 (4): 726–40. PMC 1682948. PMID 2014798.
• Thiesen HJ (1991). "Multiple genes encoding zinc finger domains are expressed in human T cells". New Biol. 2 (4): 363–74. PMID 2288909.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Gao Y, Kobayashi H, Ganss B (2004). "The human KROX-26/ZNF22 gene is expressed at sites of tooth formation and maps to the locus for permanent tooth agenesis (He-Zhao deficiency)". J. Dent. Res. 82 (12): 1002–7. doi:10.1177/154405910308201213. PMID 14630903. S2CID 22367131.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

• ZNF22+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

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