CS-27349

In this article, we will delve into the fascinating world of CS-27349. We will explore its origins, its impact on current society and possible future developments related to this topic. From its inception to the present, CS-27349 has aroused great interest in various areas, attracting both experts and people interested in better understanding its relevance. Throughout these pages, we will analyze its many facets and how it has influenced people's lives. Without a doubt, CS-27349 is a topic that will not leave anyone indifferent, and we are sure that this article will be of great interest to all those who wish to learn more about it.

CS-27349
Identifiers
  • (1R,2R,5S)-8-Methyl-8-azabicyclooct-2-yl hydroxy(diphenyl)acetate
CAS Number
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H25NO3
Molar mass351.446 g·mol−1
3D model (JSmol)
  • CN1C2CC(C1CC2)OC(=O)C(C3=CC=CC=C3)(C4=CC=CC=C4)O.Cl
  • InChI=1S/C22H25NO3/c1-23-18-12-14-19(23)20(15-13-18)26-21(24)22(25,16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-20,25H,12-15H2,1H3/t18?,19?,20-/m1/s1
  • Key:LSJGAYNIIMEDLR-SOAGJPPSSA-N

CS-27349, or L-2-α-tropinyl benzilate, is an experimental incapacitating agent. It acts as an antagonist to muscarinic acetylcholine receptors, causing delirium. It has 37% of the potency of the related compound 3-quinuclidinyl benzilate (BZ) in producing peripheral effects, but 85% of the potency in producing central effects. The mean dose required to incapacitate subjects was 1.2 times that of BZ. It has not been in use since the 1970s, and there have been no publications about its effects or long-term toxicology since then.

References

  1. ^ Ball JC (2015). "Dual Use Research of Concern: Derivatives of 3-Quinuclidinyl Benzilate". Military Medical Science Letters. 84 (1): 2–41. doi:10.31482/mmsl.2015.001.
  2. ^ Assessment of Potential Long-Term Health Effects on Army Human Test Subjects of Relevant Biological and Chemical Agents, Drugs, Medications and Substances (PDF) (Report). Ho-Chunk Technical Solutions Healthcare Division. February 29, 2016. Archived (PDF) from the original on December 25, 2020.


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