In today's article we are going to analyze the importance of Baicalin in our current society. Baicalin is a topic that has acquired great relevance in recent years, generating debate and controversy in different areas. Throughout history, Baicalin has been fundamental in people's lives, influencing their way of thinking, acting and relating to their environment. In this article, we will explore different aspects related to Baicalin, from its impact on culture and society to its role in personal and professional development. Additionally, we will examine the ethical and moral implications of Baicalin, as well as its potential to generate positive changes in the world. Without a doubt, Baicalin is a topic that deserves our attention and reflection, so we hope that this article serves as a starting point to deepen its study and understanding.
Names | |
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IUPAC name
5,6-Dihydroxy-4-oxoflav-2-en-7-yl β-D-glucopyranosiduronic acid
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Systematic IUPAC name
(2S,3S,4S,5R,6S)-6--3,4,5-trihydroxyoxane-2-carboxylic acid | |
Other names
Baicalein 7-O-glucuronide; 5,6-Dihydroxy-4-oxygen-2-phenyl-4H-1-benzopyran-7-β-D-glucopyranose acid
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Identifiers | |
3D model (JSmol)
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70480 | |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.133.557 |
EC Number |
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KEGG | |
PubChem CID
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UNII | |
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Properties | |
C21H18O11 | |
Molar mass | 446.364 g·mol−1 |
Melting point | 202 to 205 °C (396 to 401 °F; 475 to 478 K) |
Hazards | |
GHS labelling: | |
Warning | |
H315, H319, H335 | |
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).
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As baicalin is a flavone glycoside, it is a flavonoid. It is the glucuronide of baicalein.
Baicalin is found in several species in the genus Scutellaria, including Scutellaria baicalensis, and Scutellaria lateriflora. There are 10 mg/g baicalin in Scutellaria galericulata leaves. It is also present in the bark isolate of the Oroxylum indicum tree.
Baicalin is one of the chemical ingredients of at least two herbal supplements: Shuanghuanglian and Sho-Saiko-To, which is a Chinese classic herbal formula, and listed in Japan as Kampo medicine.[citation needed]
Baicalin, along with its aglycone baicalein, is a positive allosteric modulator of the benzodiazepine site and/or a non-benzodiazepine site of the GABAA receptor. In mice, baicalin produces anxiolytic effects without sedative or myorelaxant effects. It is thought that baicalin, along with other flavonoids, may underlie the anxiolytic effects of S. baicalensis and S. lateriflora.
Baicalin is a known prolyl endopeptidase inhibitor. It induces apoptosis in pancreatic cancer cells.