Triflubazam

In today's world, Triflubazam is a topic that has gained great relevance and has aroused the interest of academics, professionals and the general public. From its origins to its current evolution, Triflubazam has been the subject of numerous debates and discussions about its impact on society, the economy and politics. In this article, we will explore the different aspects of Triflubazam, from its historical importance to its influence on the contemporary world. We will analyze how Triflubazam has shaped the way we think, act and relate to our environment, and examine the relevance it has in the modern world. Through a multidisciplinary approach, we aim to shed light on this phenomenon and offer a comprehensive view of Triflubazam and its meaning in the current context.

Triflubazam
Identifiers
  • 1-methyl-5-phenyl-7-(trifluoromethyl)-1H-1,5-benzodiazepine-2,4(3H,5H)-dione
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H13F3N2O2
Molar mass334.298 g·mol−1
3D model (JSmol)
  • FC(F)(C1=CC(N(C2=CC=CC=C2)C(CC(N3C)=O)=O)=C3C=C1)F
  • InChI=1S/C17H13F3N2O2/c1-21-13-8-7-11(17(18,19)20)9-14(13)22(16(24)10-15(21)23)12-5-3-2-4-6-12/h2-9H,10H2,1H3 checkY
  • Key:DMNPCIKBNDKNTO-UHFFFAOYSA-N checkY
  (verify)

Triflubazam is a drug which is a 1,5-benzodiazepine derivative, related to clobazam. It has sedative and anxiolytic effects, with a long half-life and duration of action.

See also

References

  1. ^ US 3660381, Karl-Heinz Weber KH, Merz H, K Zeile, Giesemann R, Danneberg P, "5-Aryl-1H-1,5-benzodiazepine-2,4-diones", issued 2 May 1972, assigned to CH Boehringer Sohn AG and Co KG 
  2. ^ Lundbeck Institute (2003). "triflubazam". psychotropics.dk. Retrieved 17 November 2010.
  3. ^ Itil TM, Akpinar S, Fink M, Polvan N, Huque M, Sungurbey K (March 1976). "Controlled clinical and quantitative EEG studies of triflubazam (ORF 8063) in patients with anxiety syndrome". Current Therapeutic Research, Clinical and Experimental. 19 (3): 307–15. PMID 5248.
  4. ^ Csanalosi I, Pereira-Oran J, Case G, et al. (1977). "Triflubazam (ORF 8063), a new benzodiazepine in anxiety neurosis". Current Therapeutic Research. 22: 166–171.
  5. ^ Nicholson AN, Stone BM, Clarke CH (October 1977). "Effect of the 1,5-benzodiazepines, clobazam and triflubazam, on sleep in man". British Journal of Clinical Pharmacology. 4 (5): 567–72. doi:10.1111/j.1365-2125.1977.tb00787.x. PMC 1429140. PMID 20917.


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