Brallobarbital
In this article, we are going to address the topic of Brallobarbital, which has captured the attention of many in recent times. Brallobarbital is a topic that has generated controversy and debate, arousing great interest both in the academic community and in society in general. Throughout this article, we will explore the different aspects related to Brallobarbital, from its origin and evolution, to its impact in different areas. Additionally, we will analyze the possible implications and consequences that Brallobarbital may have in the future. Without a doubt, Brallobarbital is a topic that deserves deep reflection and analysis, so it is crucial to increase our understanding of it.
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| Other names | Brallobarbital |
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| ECHA InfoCard | 100.008.387 |
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| Formula | C10H11BrN2O3 |
| Molar mass | 287.113 g·mol−1 |
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Brallobarbital was a barbiturate developed in the 1920s. It has sedative and hypnotic properties, and was used for the treatment of insomnia. Brallobarbital was primarily sold as part of a combination product called Vesparax, composed of 150 mg secobarbital, 50 mg brallobarbital and 50 mg hydroxyzine. The long half-life of this combination of drugs tended to cause a hangover effect the next day, and Vesparax fell into disuse once newer drugs with lesser side effects had been developed. Vesparax reportedly was the drug that musician Jimi Hendrix supposedly overdosed on and led to his untimely death. It is no longer made.
References
- ^ US 1869666
- ^ Lhermann J (March 1964). "Clinical application of a new very active hypnotic associating sodium secobarbital, calcium brallobarbital and hydroxyzine (UC-8130)". Gazette Médicale de France (in French). 71: 961–2. PMID 14142825.
- ^ Yih TD, Rossum JM (June 1976). "Peculiar pharmacokinetics of brallobarbital as a source of complications in Vesparax intoxication". Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 6 (6): 355–62. doi:10.3109/00498257609151647. PMID 969563.
- ^ Fischbach R (February 1983). "Efficacy and safety of midazolam and vesparax in treatment of sleep disorders". British Journal of Clinical Pharmacology. 16 (S1): 167S–171S. doi:10.1111/j.1365-2125.1983.tb02290.x. PMC 1428085. PMID 6138072.
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