Phenylsilatrane

In today's world, Phenylsilatrane has become a highly relevant issue that impacts different aspects of daily life. Since its appearance, Phenylsilatrane has generated debates, controversies and has marked a before and after in the way in which people perceive and confront certain situations. Its influence has extended to various areas, from politics to popular culture, and its presence in today's society is undeniable. In this article, we will explore in detail the impact and importance of Phenylsilatrane, analyzing its relevance in different contexts and offering a comprehensive view on its role in today's world.

Phenylsilatrane
Stereo structural formula of phenylsilatrane
Names
Preferred IUPAC name
(TBPY-5-23)-8-Phenyltetrahydro-4H-4λ5-8,4-(epoxyethano)oxazasilolooxazasilol-4-ylium-8-uide
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.016.603 Edit this at Wikidata
UNII
  • InChI=1S/C12H17NO3Si/c1-2-4-12(5-3-1)17-13(6-9-14-17,7-10-15-17)8-11-16-17/h1-5H,6-11H2
    Key: LDOWJVBCZRHOKX-UHFFFAOYSA-N
  • C1C23CCO2(O1)(OCC3)C1=CC=CC=C1
Properties
C12H17NO3Si
Molar mass 251.357 g·mol−1
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Toxic
Except where otherwise noted, data are given for materials in their standard state (at 25 °C , 100 kPa).

Phenylsilatrane is a convulsant chemical which has been used as a rodenticide. Phenylsilatrane and some of its analogs with 4-substituents of H, CH3, Cl, Br, and CSi(CH3)3 are highly toxic to mice. They have been observed in the laboratory to inhibit the 35S-tert-butylbicyclophosphorothionate (TBPS) binding site (GABA-gated chloride channel) of mouse brain membranes.

See also

References

  1. ^ Voronkov MG (1966). "Silatranes: Intra-Complex Heterocyclic Compounds of Pentacoordinated Silicon" (pdf). Pure and Applied Chemistry. 13 (1–2): 35–60. doi:10.1351/pac196613010035.
  2. ^ Lukevics E, Ignatovich L, Khokhlova L, Belyakov S (1997). "Synthesis, Structure, and Toxicity of Arylgermatranes". Chemistry of Heterocyclic Compounds. 33 (2): 239–241. doi:10.1007/BF02256767.
  3. ^ Horsham MA, Palmer CJ, Cole LM, Casida JE (1990). "4-Alkynylphenylsilatranes: Insecticidal Activity, Mammalian Toxicity, and Mode of Action". Journal of Agricultural and Food Chemistry. 38 (8): 1734–1738. doi:10.1021/jf00098a023.


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